Results 71 to 80 of about 9,762,870 (295)

Corrigendum to “Systematic evidence map (SEM) template: Report format and methods used for the US EPA Integrated Risk Information System (IRIS) program, Provisional Peer Reviewed Toxicity Value (PPRTV) program, and other “fit for purpose” literature-based human health analyses” [Environ. Int. 169 (2022) 107468]

Environment International, 2023
Kristina A. Thayer, Michelle Angrish, Xabier Arzuaga, Laura M. Carlson, Allen Davis, Laura Dishaw, Ingrid Druwe, Catherine Gibbons, Barbara Glenn, Ryan Jones, J. Phillip Kaiser, Channa Keshava, Nagalakshmi Keshava, Andrew Kraft, Lucina Lizarraga, Amanda Persad, Elizabeth G. Radke, Glenn Rice, Brittany Schulz, Rachel M. Shaffer, Teresa Shannon, Andrew Shapiro, Shane Thacker, Suryanarayana V. Vulimiri, Antony J. Williams, George Woodall, Erin Yost, Robyn Blain, Katherine Duke, Alexandra E. Goldstone, Pam Hartman, Kevin Hobbie, Brandall Ingle, Courtney Lemeris, Cynthia Lin, Alex Lindahl, Kristen McKinley, Parnian Soleymani, Nicole Vetter   +38 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Report on Methodological Quality Assessment of Primary Care and General Practice Research in China in 2021: Qualitative and Mixed Methods Research Section [PDF]

Zhongguo quanke yixue
Background General practice has significant interdisciplinary characteristics, both qualitative research and mixed methods research are applicable to scientific research in this field.
Quality Assessment Group for Qualitative and Mixed Methods Research of Chinese General Practice
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Evaluation of Immunotoxicity Induced by Organophosphorus Pesticide Malathion

Toxics
Malathion (MLT) is an organophosphate pesticide widely used worldwide. Due to its environmental persistence and accumulation in living organisms, concerns have been raised regarding its potential health effects beyond the classical mechanism of ...
Weichunbai Zhang, Minhan Lou, Ling Yong, Xiao Xiao, Chunlai Liang, Wei Wang, Hui Yang, Xudong Jia, Yin Wang, Yan Song   +9 more
doaj   +1 more source

Virological assessment of hospitalized patients with COVID-2019

Nature, 2020
R. Wölfel, V. Corman, W. Guggemos, M. Seilmaier, S. Zange, M. Müller, Daniela Niemeyer, T. Jones, P. Vollmar, C. Rothe, M. Hoelscher, T. Bleicker, Sebastian Brünink, J. Schneider, R. Ehmann, K. Zwirglmaier, C. Drosten, C. Wendtner   +17 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Co-Occurrence of Beauvericin and Enniatins in Edible Vegetable Oil Samples, China

Toxins, 2019
A total of 470 edible vegetable oil samples including peanut, soybean, rapeseed, sesame seed, corn, blend, and others collected from eight provinces of China were analyzed for the concentrations of beauvericin (BEA), enniatin A (ENA), A1 (ENA1), B (ENB),
Xiaomin Han, Wenjing Xu, Jing Zhang, Jin Xu, Fengqin Li   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source