Results 251 to 260 of about 3,816,397 (298)

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini   +28 more
wiley   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Policy Assessment Methodology

open access: yes
D61 Policy Assessment Methodology Report describing the proposed methodology and the stakeholders involved in each case studyDelivery date ...
openaire   +1 more source
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Assessing Research Methodology

Sociological Methods & Research, 1977
This paper reports the development and application of a method for evaluating the methodology of social science research. In this study, 11 social scientists rated the methodology of 126 federally sponsored, social science research projects. Written documentation from each research project was divided into three packets, representing three stages of ...
Donald G. McTavish   +4 more
openaire   +1 more source

Assessment of clinical testing methodology

Contraception, 1975
Because inadequate clinical testing may expose the public to unwarranted toxic effects a review of current clinical testing methodology is made and recommendatiosn for improvements are given. Areas covered include evaluation of data analysis procedures evaluation of the role of research design and some specific problems in contraceptive method ...
openaire   +2 more sources

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