Results 111 to 120 of about 1,588,707 (264)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Assessment [PDF]

open access: yesJournal of the Royal Society of Medicine, 2005
openaire   +2 more sources

Applying curricula design principles to enhance students learning experience via in-class formative assessments

open access: yes, 2016
This research is focused on investigating the application of curricula design theories as means to improve the delivery of materials for Human Resource Management(HRM) subject in HND programmes.
Elezi, E.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Strengthening infection prevention and control in humanitarian settings: lessons and opportunities from Médecins Sans Frontières (2021-2023). [PDF]

open access: yesBMJ Glob Health
Broomand A   +10 more
europepmc   +1 more source

and skipjack stock assessments

open access: yes, 2011
A tag reporting rate is a critical parameter required for modelling tag recapture data and defines the probability that a tag is returned, given that a tagged fish was recaptured.
Skipjack   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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