Advanced Science, EarlyView.This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou +19 more
wiley +1 more source
The Potential Role For CDFIs in the Opportunity Zones of the Investing in Opportunities Act (IIOA) [PDF]
, 2019 The Opportunity Zones legislation was designed to mobilize new levels of capital into low- and moderate-income (LMI) communities – areas that have historically been overlooked and underserved by mainstream capital markets.
Swack, Michael, Tansey, Charles
core +1 more source
Advanced Science, EarlyView.In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen +15 more
wiley +1 more source
Connecting Tax Time to Financial Security: Designing Public Policy with Evidence from the Field [PDF]
, 2014 The ability to accumulate and access savings is a fundamental determinant of economic security for many families, especially those with low incomes and limited resources.
Elliott Schruer, Rachel Black
core
Advanced Science, EarlyView.To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li +9 more
wiley +1 more source
Addressing Disparities in Alzheimer's Disease and African-American Participation in Research: An Asset-Based Community Development Approach. [PDF]
Front Aging Neurosci, 2019 Green-Harris G +7 more
europepmc +1 more source
Building Community Assets: Growing Lower-Income Credit Union Membership through Community and Credit Union Partnerships [PDF]
, 2008 This report details the partnership process and lessons learned from a two-year technical assistance program designed to help community organizations partner with mainstream credit unions with the goal of enrolling new lower-income members or expanding ...
Marva Williams, Sarah Duda, Tom Feltner
core
Integrating Spatial Proteogenomics in Cancer Research
Advanced Science, EarlyView.Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Can Asset-Based Community Development with Children and Youth Enhance the Level of Participation in Health Promotion Projects? A Qualitative Meta-Synthesis. [PDF]
Int J Environ Res Public Health, 2019 Agdal R, Midtgård IH, Meidell V.
europepmc +1 more source
A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application
Advanced Science, EarlyView.This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu +5 more
wiley +1 more source