Results 101 to 110 of about 1,523,306 (304)

The Asset-By-Asset Poverty Index

Journal of Income Distribution®, 2012
This article pioneers an asset-by-asset point index, which represents a simple methodology that uses inputs rather than outputs of well-being to recognise the 'poor' on a point basis, household by household. It focuses on assets, which are a significant aspect of well-being in whose absence households may fall into deprivation.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comparing the financial benefits of different grain production systems in South Africa’s summer rainfall region

South African Journal of Science
There is growing evidence that soil degradation, among other factors, has led to both the decline and constraint of agriculture in southern Africa. Conservation and regenerative agriculture (CA/RA) have been proposed as a grain crop production system ...
Mary Maluleke, Nic van Schalkwyk, Anika de Beer, Hendrik Smith, James Blignaut, Jaap Knot, Gerrie Trytsman, Liane Erasmus   +7 more
doaj   +1 more source

Index for asset value measure obtained from condition monitoring digitalized data interpretation. A railway asset management application [PDF]

, 2019
Hosted by the Johannes Kepler University, Linz, Austria. May 23-24, 2019The objective of any asset is to provide value to the organization, being the corner stone to get a highest possible economic benefit in a sustainable way. An effective asset value
Candón, Eduardo, Crespo Márquez, Adolfo, Fuente, Antonio de la, González, Pablo, Guillén López, Antonio Jesús, Martínez-Galán, Pablo   +5 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Measuring Monetary Conditions in US Asset Markets - A Market Specific Approach [PDF]

We analyze monetary conditions in US asset markets — corporate equity, real estate, Treasury bond and corporate & foreign bond — from a market specific perspective, proposing the concept of market leverage.
Drescher, Christian, Herz, Bernhard
core   +1 more source

Outperforming the S&P 500 Using Top-Down Asset Allocation [PDF]

, 2016
This paper investigates whether portfolio managers can outperform the S&P 500 index using top-down asset allocation, using historical returns, standard deviations, and correlations of different asset classes.
Lanier, Benjamin
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Assets, ‘Asset-ness’ and Graduation

IDS Bulletin, 2015
Asset-based approaches – usually involving asset transfers and/or asset building – are increasingly central to thinking about poverty alleviation, social protection, graduation and livelihood resilience. Although the notion of assets is well established in the literature, the meanings of and relationships between asset(s), livelihood capital(s), risks ...
Sung Kyu Kim, James Sumberg
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source