Results 31 to 40 of about 345,919 (279)

Research on the impact and heterogeneity of housing on the allocation of financial assets of households: Evidence from China

open access: yesHeliyon
This paper investigates the impact of housing with both consumption and investment attributes on the risky financial asset allocation of households, constructs Probit and Tobit models using 2019 China Household Finance Survey (CHFS) data, and proceeds to
Lili Wu, Hui Yu
doaj   +1 more source

Take Bitcoin into your portfolio: a novel ensemble portfolio optimization framework for broad commodity assets

open access: yesFinancial Innovation, 2021
The emergence and growing popularity of Bitcoins have attracted the attention of the financial world. However, few empirical studies have considered the inclusion of the newly emerged commodity asset in the global commodity market.
Yuze Li   +3 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Simul-RL Portfolio Framework: Black-Scholes-Merton and Reinforcement Learning for Asset Allocation

open access: yesIEEE Access
Asset allocation method using reinforcement learning is being actively researched. However, the existing asset allocation methods do not consider the following viewpoints in solving the asset allocation problem.
Jungyu Ahn, Hyoung-Goo Kang
doaj   +1 more source

Real estate in the mixed-asset portfolio: the question of consistency [PDF]

open access: yes, 2004
The recent poor performance of the equity market in the UK has meant that real estate is increasingly been seen as an attractive addition to the mixed-asset portfolio. However, determining whether the good return enjoyed by real estate is a temporary or
Lee, Stephen, Stevenson, Simon
core  

Risk aversion under preference uncertainty [PDF]

open access: yes, 2010
We show that if an agent is uncertain about the precise form of his utility function, his actual relative risk aversion may depend on wealth even if he knows his utility function lies in the class of constant relative risk aversion (CRRA) utility ...
Kräussl, Roman   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Asset Allocation Strategies Using Covariance Matrix Estimators

open access: yesActa Universitatis Sapientiae: Economics and Business, 2022
The covariance matrix is an important element of many asset allocation strategies. The widely used sample covariance matrix estimator is unstable especially when the number of time observations is small and the number of assets is large or when high ...
László PáL
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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