Results 31 to 40 of about 348,165 (301)

Multi-Asset Multi-Agent Reinforcement Learning for Portfolio Management

open access: yesIEEE Access
Portfolio management reduces the risks and improves the profits of a portfolio comprising various asset classes (including stocks, bonds, commodities, and cash) that exhibit low correlations and distinct risk-return characteristics.
Sang-Ho Kim, Ki-Hoon Lee
doaj   +1 more source

Research on the impact and heterogeneity of housing on the allocation of financial assets of households: Evidence from China

open access: yesHeliyon
This paper investigates the impact of housing with both consumption and investment attributes on the risky financial asset allocation of households, constructs Probit and Tobit models using 2019 China Household Finance Survey (CHFS) data, and proceeds to
Lili Wu, Hui Yu
doaj   +1 more source

Hopfield networks for asset allocation

open access: yesProceedings of the 5th ACM International Conference on AI in Finance
We present the first application of modern Hopfield networks to the problem of portfolio optimization. We performed an extensive study based on combinatorial purged cross-validation over several datasets and compared our results to both traditional and deep-learning-based methods for portfolio selection.
Carlo Nicolini   +3 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Take Bitcoin into your portfolio: a novel ensemble portfolio optimization framework for broad commodity assets

open access: yesFinancial Innovation, 2021
The emergence and growing popularity of Bitcoins have attracted the attention of the financial world. However, few empirical studies have considered the inclusion of the newly emerged commodity asset in the global commodity market.
Yuze Li   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Simul-RL Portfolio Framework: Black-Scholes-Merton and Reinforcement Learning for Asset Allocation

open access: yesIEEE Access
Asset allocation method using reinforcement learning is being actively researched. However, the existing asset allocation methods do not consider the following viewpoints in solving the asset allocation problem.
Jungyu Ahn, Hyoung-Goo Kang
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Asset Allocation in Transition Economies [PDF]

open access: yesSSRN Electronic Journal, 2002
Designing an investment strategy in transition economies is a difficult task, because stock markets opened through time, time series are short, and there is little guidance how to obtain expected returns and covariance matrices necessary for mean-variance asset allocation.
Jondeau, E., Rockinger, M.
openaire   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

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