Results 61 to 70 of about 1,037,455 (301)

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

KINERJA PENGELOLAAN DANA PADA PASAR MODAL INDONESIA

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2008
The mutual fund is a fast growing, flexible and sizely attainable product, hence make it as favourable choice for the investors. As in other developing countries, however, the management of the fund invested in mutual fund is done by pointed fund manager.
Yuyun Istavirti   +2 more
doaj   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

open access: yesAdvanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao   +18 more
wiley   +1 more source

Asset allocation under multivariate regime switching [PDF]

open access: yes
This paper studies asset allocation decisions in the presence of regime switching in asset returns. We find evidence that four separate regimes - characterized as crash, slow growth, bull and recovery states - are required to capture the joint ...
Massimo Guidolin, Allan Timmerman
core  

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

The importance of strategic asset allocation

open access: yes, 2013
This paper examines the impact of strategic asset allocation on total returns of investment portfolios. It aims to confirm the results of previous studies using US investment data that found strategic asset allocation dominating the other investment ...
Santacruz, Lujer
core   +1 more source

Impact of departure audit of natural resource assets on land resource allocation efficiency and its mechanisms: A perspective of land supply behavior [PDF]

open access: yesZiyuan Kexue
[Objective] As an institutional innovation in the national governance system, exploring the impact of natural resource asset departure audit on land resource allocation efficiency and its mechanism is of great significance for continuously advancing such
YANG Lili, WEN Longjiao, WANG Jian
doaj   +1 more source

Strategic Asset Allocation, Asset Price Dynamics, and the Business Cycle [PDF]

open access: yes
The main contribution of this work is to provide a dynamic general equilibrium model of asset allocation, allowing to reconcile economic theory with several puzzling contradictions recently pointed out in the literature: (i) the asset allocation puzzle, (
Ivan Jaccard
core  

Optimal Asset Allocation with Factor Models for Large Portfolios [PDF]

open access: yes, 2008
This paper characterizes the asymptotic behaviour, as the number of assets gets arbitrarily large, of the portfolio weights for the class of tangency portfolios belonging to the Markowitz paradigm.
M. Hashem Pesaran   +3 more
core   +2 more sources

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