Results 121 to 130 of about 565,001 (307)

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

open access: yesAdvanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber   +12 more
wiley   +1 more source

Solutions for Impact Investors: From Strategy to Implementation [PDF]

open access: yes, 2009
In writing this monograph, our main goal is to provide impact investors with tools to tighten the link between their investment decisions and impact creation.
Albert V. Brun   +5 more
core  

Structural Eigenmodes of the Brain to Improve the Source Localization of EEG: Application to Epileptiform Activity

open access: yesAdvanced Science, EarlyView.
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu   +6 more
wiley   +1 more source

Impact at Scale: Policy Innovation for Institutional Investment With Social and Environmental Benefit [PDF]

open access: yes, 2012
Explores policy options to maximize impact investing opportunities for institutional investors and accelerate the development of impact investing practices and products.
Ben Thornley, David Wood, Katie Grace
core  

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

open access: yesAdvanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao   +6 more
wiley   +1 more source

Community Empowerment Based on Asset- Based Community Development in Enhancing Environmental Awareness and Income of Forest Farmer Groups

open access: yesJournal of Community Service and Empowerment
This research aims to (1) describe of forest farmers empowerment, (2) analyze changes in forest farmers behavior in management and preserving forest ecosystems as a result of empowerment activities, and (3) analyze the contribution of local resource ...
Tri Cahyono Putra   +1 more
doaj   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

open access: yesAdvanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu   +12 more
wiley   +1 more source

Strategies for Successfully Marketing and Stabilizing the Occupancy of Mixed-Income/Mixed-Race Properties: A Case Study of Cedar Road Apartments in Vista, California [PDF]

open access: yes, 2005
Cedar Road is a 40-unit mixed income, mixed-race property in Vista, California. Vista is a fast growing city 35 miles north of San Diego. Its population grew 29 percent between 1990 and 2003 and almost all of that growth has been in the Hispanic ...
Judy Weber
core  

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang   +8 more
wiley   +1 more source

NEGOTIATING SERVICE LEARNING THROUGH COMMUNITY ENGAGEMENT: ADAPTIVE LEADERSHIP, KNOWLEDGE, DIALOGUE AND POWER

open access: yesEducation as Change, 2016
This article builds on two recent publications (Preece 2013; 2013a) concerning the application of asset-based community development and adaptive leadership theories when negotiating university service learning placements with community organisations in ...
Julia Preece
doaj  

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