Results 141 to 150 of about 3,417 (188)

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal   +14 more
wiley   +1 more source

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li   +7 more
wiley   +1 more source

Development and Validation of Scalable Energy Models for Battery Cell Production Processes

open access: yesEnergy Technology, EarlyView.
Battery cell production is characterized by energy‐intensive processes that contribute significantly to the overall environmental impact of the battery life cycle. Therefore, this work describes process‐specific energy models for the different manufacturing steps. Validation and sensitivity analysis of the different models are presented together with a
Daniel Perez Clos   +5 more
wiley   +1 more source

Sustainable Solid Polymer Electrolytes Based on NaCMC‐PVA Blends for Energy Storage Applications: Electrical and Electrochemical Insights with Application to Electric Double‐Layer Capacitors

open access: yesEnergy Technology, EarlyView.
A novel biopolymer electrolyte using sodium carboxymethyl cellulose/polyvinyl alcohol and NaPF6 enhances ionic conductivity and electrochemical stability for electric double‐layer capacitors. Conductivity peaks at 35 wt% salt before declining due to ion clustering. Structural and electrochemical analyses confirm promising device performance.
Vipin Cyriac   +5 more
wiley   +1 more source

Decentralized Wind Energy Systems as Catalysts for Urban Resilience: A Design Framework

open access: yesEnergy Science &Engineering, EarlyView.
ABSTRACT Confronting the escalating extreme weather events (EWEs) and intensifying winds, this study proposes an active response to these issues by exploring decentralized wind energy production for Peng Chau Island, Hong Kong. It integrates theoretical perspectives on energy democracy—empowering local communities through energy autonomy—and urban ...
Tian Cheng
wiley   +1 more source

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