Results 111 to 120 of about 7,298,134 (293)

Asset prices and fiscal balances [PDF]

open access: yes
The paper argues that there are important links between asset prices and public finances which can strongly affect the variability of fiscal balances.
Schuknecht, Ludger, Eschenbach, Felix
core  

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

What Determines Expected International Asset Returns? [PDF]

open access: yes
This paper characterizes the forces that determine time-variation in expected international asset returns. We offer a number of innovations. By using the latent factor technique, we do not have to prespecify the sources of risk.
Campbell R. Harvey   +2 more
core  

Composite degradation index reveals type-specific drivers of forest decline on Qinghai-Tibet Plateau

open access: yesEnvironmental and Sustainability Indicators
Forest degradation assessments are constrained by single-dimensional indicators (e.g., NDVI) that fail to simultaneously capture functional degradation (biomass loss) and structural degradation (landscape fragmentation), while type-specific management ...
Huoyan Zhou   +4 more
doaj   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Asset Price Shocks, Real Expenditures, and Financial Structure: A Multi-Country Analysis [PDF]

open access: yes
This paper examines the responses of private consumption, residential investment, and business investment in 11 EU countries, Japan, and the United States to shocks in housing and equity prices.
Leo de Haan   +2 more
core  

Asset structure mismatch and corporate carbon risk

open access: yesDiscover Sustainability
With the implementation of the dual-carbon strategy, carbon risk has emerged as a critical consideration for corporate operations. Compounding this, the persistent and growing asset structure mismatch presents a significant threat to corporate ...
Fubi Luo, Min Liao, Tingwei Luo
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Asset allocation under multivariate regime switching [PDF]

open access: yes
This paper studies asset allocation decisions in the presence of regime switching in asset returns. We find evidence that four separate regimes - characterized as crash, slow growth, bull and recovery states - are required to capture the joint ...
Massimo Guidolin, Allan Timmerman
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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