Results 71 to 80 of about 62,254 (306)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Production Based Asset Pricing [PDF]
This paper exploits producer's first order conditions to link asset prices to data on investment, output, etc. through marginal rates of transformation, just as consumer's first order conditions are commonly used to link asset prices to consumption data ...
John H. Cochrane
core
Profit: Jurnal Administrasi Bisnis, 2016 The objectives of the research are to analyze the influence of capital structure and asset management on profitability and firm value of real estate and property that listed in Indonesia Stock Exchange for the period of 2011-2013 and give recommendations
Eka Agustiningtias +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Intertemporal asset allocation strategies under inflationary risk
, 2006 Hsiao C-Y. Intertemporal asset allocation strategies under inflationary risk. Bielefeld (Germany): Bielefeld University; 2006.In the framework of the intertemporal asset allocation problem, this dissertation focuses on the modelling of inflation risk and
Hsiao, Chih-Ying
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Asset Pricing Under The Quadratic Class [PDF]
We identify and characterize a class of term structure models where bond yields are quadratic functions of the state vector. We label this class the quadratic class and aim to lay a solid theoretical foundation for its future empirical application.
Markus Leippold, Liuren Wu
core
Analyzing enterprise asset structure and profitability using cloud computing and strategic management accounting. [PDF]
PLoS One, 2021 Shi W.
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
PENGARUH STRUKTUR ASET DAN STRUKTUR MODAL TERHADAP CASH FLOW SHOCK
Akuntansi Dewantara, 2018 The purpose of this study is to determine the effect of asset structure and capital structure on cash flow shock. This research is classified as causality research.
Dewi Kusuma Wardani +1 more
doaj +1 more source