Results 101 to 110 of about 495,380 (316)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
U.S. food processing sector assets are valued at about $360 billion, or about 12 percent of all manufacturing assets. Profit and sales returns on assets in food processing are among the highest in the U.S. economy. Foreign holdings comprise a significant
Gallo, Anthony E.
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Cover ASSETS: JAP Vol 10, No 2 (2021)
, 2021 Jurnal Akuntansi dan Pendidikan, ASSETS
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Management of Intangible Assets [PDF]
In a society marked by economic crisis, creating value and market competition becomes a heady company need. According to recent studies, in competitive companies, the highest share in the assets is hold by the value of intangible assets.
Ioan BIRCEA, Noemi Iuliana BIRCEA
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Reusable SOA Assets Identification Using E-Business Patterns
, 2009 Keyword-based search techniques are currently used to identify assets packaged for reuse. Unfortunately, these techniques are not suitable for searching large asset repositories, as they are known of having low precision and recall.
Elgedawy, Islam, Islam Elgedawy
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Criminal Assets Bureau strategic plan 2020 –2023. [PDF]
, 2020 The Criminal Assets Bureau (the Bureau) Strategic Plan 2020 - 2023 sets out our priorities and how we plan to carry out our mission ‘’to ensure crime does not pay” over this four year period. Following a review of our accomplishments over the lifetime of
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Assets at Marriage in Rural Ethiopia [PDF]
This paper examines the determinants of assets at marriage in rural Ethiopia. We identify and test three separate processes that determine assets brought to marriage: assortative matching; compensating parental transfers at marriage; and strategic ...
Agnes Quisumbing, Marcel Fafchamps
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