Results 31 to 40 of about 116,983 (244)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Soil microbial networks’ complexity as a primary driver of multifunctionality in photovoltaic power plants in the northwest region of China

Frontiers in Microbiology
IntroductionExploiting photovoltaic power generation as a novel source of clean energy has become increasingly common in recent times. Nevertheless, the impact of photovoltaic power plants (PVs) on soil microbial activity and several functions is unclear.
Liuqing Zhao, Sumeng Xu, Sumeng Xu, Jinmei Zhao, Shujuan Chen, Xiaolong Liu, Xiuyuan Zheng, Xiuhui Wang, Zhao Zhu, Fei Gao, Bingzhe Fu, Shuxia Li   +11 more
doaj   +1 more source

Cost analysis of blood purification: a tool for decision-making and supply chain optimization

Renal Replacement Therapy, 2019
This study complies with the reorganization of health care provider processes based on the cost of life cycle of the product. The aim is to determine the costs of treatment administration of extracorporeal dialysis and other treatments in extracorporeal ...
Silvia Grazzini, Claudia Razzauti, Lea Paola Fabbri, Michele Galatà, Stefano Bellucci, Ilaria Colivicchi, Maria Elvira Mancino   +6 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Vulnerability of the Building Construction Safety System Based on ANP-SD [PDF]

E3S Web of Conferences
The study aims to analyze the evolution trend of system vulnerability under the interactive relationship of building construction risk factors. Based on social technology theory, the influencing factors are analyzed from four subsystems: individual ...
Chen Bin, Xiong Jing
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

The Objectives of Farm Operations—Evidence from a Region in Poland

Agriculture, 2020
The objectives set by agricultural producers directly translate into the directions of the development of farms. What is particularly important: Is there a conflict between the economic and environmental objectives of farm operations?
Aleksander Grzelak
doaj   +1 more source

Assets and assetization in financialized capitalism

Review of International Political Economy, 2020
In the wake of the global financial crisis of 2007–09, political economists have typically identified and interrogated speculative logics and credit-debt relations as the markers of financialized c...
openaire   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Americas’ Spatial Data Infrastructure

ISPRS International Journal of Geo-Information, 2019
During the last decade, the production of geospatial information has increased considerably; however, managing and sharing this information has become increasingly difficult for the organizations that produce it, because it comes from different data ...
Paloma Merodio Gómez, Macarena Pérez García, Gabriela García Seco, Andrea Ramírez Santiago, Catalina Tapia Johnson   +4 more
doaj   +1 more source