Results 231 to 240 of about 179,254 (267)

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

open access: yesAdvanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu   +7 more
wiley   +1 more source

Enhancing Biogenic Formic Acid Production in the Modified OxFA Process by Acetonitrile Addition

open access: yesAdvanced Science, EarlyView.
In this study, the beneficial effect of using acetonitrile as a co‐solvent in the modified OxFA process is shown, outperforming methanol, demonstrating improved reaction kinetics combined with high selectivity for the HPA‐2 (H5PV2Mo10O40) catalyzed oxidation of xylose to FA.
Jan‐Dominik H. Krueger   +7 more
wiley   +1 more source

Diffusion‐Based Generative Model With Scaffold‐Hopping Strategy Yields Highly Potent Bioactive Molecules

open access: yesAdvanced Science, EarlyView.
SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang   +8 more
wiley   +1 more source

The effect of general practitioners' sex and age on patients' healthcare utilization: a Norwegian registry study. [PDF]

open access: yesRes Health Serv Reg
Bennett SM   +5 more
europepmc   +1 more source

Enhanced Stability in Zero‐Excess Li‐Metal Batteries via Prelithiated Carbon Nanofiber Interlayers

open access: yesAdvanced Science, EarlyView.
Carbon nanofibers carbonized at 700°C show Li metal deposition predominantly on the side facing the Cu current collector. During delithiation, Li agglomerates remain as inactive lithium on the fiber surface. This behavior can be changed by a modified n‐Buli prelithiation without a washing step, suppressing dead Li formation and therefore enabling ...
Sandro Schöner   +11 more
wiley   +1 more source

A Data‐Driven Inverse Design Methodology for Magnetic Soft Millirobots Navigating in Confined Spaces

open access: yesAdvanced Science, EarlyView.
A data‐efficient inverse design framework automates the optimization of magnetic soft millirobots for confined‐space navigation. Integrating a physics‐based Cosserat rod model with Bayesian optimization efficiently identifies high‐performance geometries.
Ziyu Ren   +5 more
wiley   +1 more source

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