Results 201 to 210 of about 77,888 (259)

Molecular detection and phylogenetic characterization of Babesia and Ehrlichia in free-living opossums from southeastern Brazil. [PDF]

Acta Parasitol
Ribeiro SR, Rodrigues LP, Mochiuti JO, Resende CEV, Gazeta GS, Borsoi AB, da Cruz MGC, Bitencourth K, Teixeira RHF, da Lima LSS.   +9 more
europepmc   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Aneurysmal systemic-to-pulmonary arterial connection mimicking MAPCA in a structurally normal adult: computed tomography angiography diagnosis and endovascular exclusion. [PDF]

Egypt Heart J
Dhakal S, Yasmine N, Karabulut N.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Management of a Pulmonary Sequestration With a Large Aberrant Artery Using a Hybrid Approach: Thoracic Endovascular Aortic Repair Followed by Video-Assisted Thoracoscopic Lobectomy. [PDF]

Case Rep Surg
Koliakos E, Charbonneau P, Liberman M, Nasir B, Gorgos AB, Ferraro P.   +5 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Delayed Diagnosis of Congenital Aortopathies: Multimodal Imaging Makes the Difference. [PDF]

JACC Case Rep
Boukheloua M, Khlidj Y, Baali A, Aroua S, Berrehal M.   +4 more
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Presence of small and large branch vessels from intracranial aneurysms increases the risk of post-treatment recurrence and retreatment following endovascular coiling: insights from a propensity score-matched cohort. [PDF]

Front Surg
Arunachalam Sakthiyendran N, Pellegrino A, McNeil EP, Barhouse P, Purohit S, Ramirez-Velandia F, Alwakaa O, Granstein JH, Ogilvy CS, Taussky P.   +9 more
europepmc   +1 more source

Laser-cut stent-assisted coil embolization for basilar apex aneurysms: a retrospective single-center study. [PDF]

Clinics (Sao Paulo)
Chen C, Lai L, Zou J, Chen Q, Zhu H, Huang J, Jiang Z.   +6 more
europepmc   +1 more source