Results 141 to 150 of about 200,361 (330)

On the topical issue of assisted dying: the insurmountable challenges of human existence, and the right to exit

Frontiers in Public Health
Although the issue of medical-assisted dying or medical aid in dying (MAID, euthanasia, and medical-assisted suicide) has a long history, it has become an increasingly important topic in recent years.
Tobore Onojighofia Tobore
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

“It is difficult to be absolutely sure one way or the other.” – a mixed method study on Finnish physicians’ views on euthanasia and physician-assisted suicide

BMC Medical Ethics
Background Euthanasia and physician-assisted suicide (PAS) are complex and ethically challenging topics. Physicians’ attitudes toward euthanasia and PAS have been studied, but little is known about their ethical considerations regarding these topics ...
Reetta P. Piili, Minna Hökkä, Elina Tolvanen, Jukka Vänskä, Pekka Louhiala, Juho T. Lehto   +5 more
doaj   +1 more source

Assisted dying [PDF]

British Journal of General Practice, 2013
openaire   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A Personal Experience with Suffering Patients: Bringing Home the Assisted Dying Debate

, 2016
Dr Rodney Syme
openalex   +2 more sources

Refractory suffering at the end of life and the assisted dying debate: An interview study with palliative care nurses and doctors

, 2020
Kristine Espegren Gustad, Åsta Askjer, Per Nortvedt, Olav Magnus S. Fredheim, Morten Magelssen   +4 more
openalex   +2 more sources

What next for voluntary assisted dying in Australia? [PDF]

, 2023
Ben White, Lindy Willmott
openalex   +1 more source

Physician-Assisted Suicide: A Common Law Roadmap for State Courts [PDF]

, 1997
Part I examines the development of the law legalizing passively hastening death and how this development relied significantly on distinguishing passively hastening death from actively hastening death.
Meisel, Alan
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source