Results 91 to 100 of about 318,953 (318)

Correlations among hope, fertility quality of life and negative emotions for couples undergoing their first in vitro fertilization–embryo transfer: a cross-sectional analysis

Reproductive Health
Background The global incidence of infertility is increasing, and infertility has become an important medical and social issue. With the widespread application of in vitro fertilization-embryo transfer (IVF-ET) technology, the mental health problems of ...
Hui Ye, Jing Zhao, Yujie Zou, Xiaorun Song, Mi Xu, Yu Zhang, Lili Zhang, Gaohua Wang   +7 more
doaj   +1 more source

Precise Personalized Medicine in Gynecology Cancer and Infertility

Frontiers in Cell and Developmental Biology, 2020
Since the conception of precision medicine has been put forward in oncology, this idea has been popularized and applied in many specialties. Significant progress has been made toward personalizing the entire process, including diagnosis, treatment ...
Pu-Yao Zhang, Pu-Yao Zhang, Pu-Yao Zhang, Yang Yu, Yang Yu, Yang Yu   +5 more
doaj   +1 more source

Assisted Reproductive Technology Surveillance — United States, 2015

Morbidity and mortality weekly report. Surveillance summaries, 2018
Problem/Condition Since the first U.S. infant conceived with assisted reproductive technology (ART) was born in 1981, both the use of ART and the number of fertility clinics providing ART services have increased steadily in the United States.
S. Sunderam, D. Kissin, Sara Crawford, S. Folger, S. Boulet, L. Warner, W. Barfield   +6 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Assisted reproductive technology: prevalence and associated factors in Southern Brazil

Revista de Saúde Pública, 2019
OBJECTIVE: To assess the prevalence of successful assisted reproductive technology and to identify the associated factors. METHODS: This population-based birth cohort study was carried out with 4,333 pregnant women expected to deliver in 2015 in the ...
Shana Ginar da Silva, Andréa Dâmaso Bertoldi, Mariângela Freitas da Silveira, Marlos Rodrigues Domingues, Kelly R Evenson, Iná Silva dos Santos   +5 more
doaj   +1 more source

Influence of the Period of Abstinence on Semen Quality in a Patient with Systemic Lupus Erythematosus: A Case Report and Review of the Literature

Case Reports in Rheumatology, 2020
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can affect fertility. There is currently little information regarding the semen profile of males with SLE.
Tarah H. B. Waters, Carol Pui Shan Chan, Tin Chiu Li, David Yiu Leung Chan   +3 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Assisted reproductive technology and the risk of preeclampsia: an updated systematic review and meta-analysis

BMC Pregnancy and Childbirth, 2019
BackgroundThe objective of this systematic review and meta-analyses was to assess the risk of preeclampsia among women who conceived with assisted reproductive technology (ART).MethodsWe searched the ISI Web of Knowledge, Medline/PubMed, Scopus, and ...
A. Almasi-Hashiani, R. Omani-Samani, M. Mohammadi, Payam Amini, Behnaz Navid, A. Alizadeh, Esmaeil Khedmati Morasae, S. Maroufizadeh   +7 more
semanticscholar   +1 more source

Luteal Phase in Assisted Reproductive Technology

Frontiers in Reproductive Health, 2020
Luteal phase (LP) is the period of time beginning shortly after ovulation and ending either with luteolysis, shortly before menstrual bleeding, or with the establishment of pregnancy.
J. Tesarik, Cristina Conde-López, M. Galán-Lázaro, Raquel Mendoza‐Tesarik   +3 more
semanticscholar   +1 more source