Results 81 to 90 of about 170,985 (294)
The Clinical Spectrum and Neurodevelopmental Pathogenesis of KPTN‐Related Disorder in a Mouse Model
Annals of Neurology, EarlyView.Objective Pathogenic variants in Kaptin (KPTN) cause KPTN‐related disorder (KRD). KPTN modulates mTOR signaling activation within the KICSTOR complex in response to cellular amino acid levels. We define the clinical spectrum and investigate the developmental pathogenesis of KRD.
Lettie E. Rawlins +104 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia +5 more
wiley +1 more source
Audience responses to representations of family-assisted suicide on British television [PDF]
, 2017 Reflecting on different generic conventions, this study highlights the strengths and weaknesses of documentaries and soap operas in addressing the societal and the personal dimensions of family-assisted suicide.
Inthorn, Sanna
core +4 more sources
Voluntary active euthanasia: Is there a place for it in modern day medicine?
South African Family Practice, 2008 This article discusses various ethical and legal concepts regarding euthanasia and includes concepts like physician assisted suicide, assisted suicide, voluntary active euthanasia, killing vs. letting die, indirect euthanasia and terminal sedation.
Gboyega A. Ogunbanjo +1 more
doaj +1 more source
Physician-Assisted Suicide: The Legal and Practical Contours [PDF]
, 1993 This paper considers current medical and legal perspectives on patients\u27 right to assistance in dying. In highlighting the competing policy objectives that must be resolved, it examines failed legislative initiatives in Washington and California.
Dangelantonio, Anthony J.
core +1 more source
Assisted stellar suicide in V617 Sgr
, 2005 V617 Sgr is a V Sagittae star - a group of binaries thought to be the galactic counterparts of the Compact Binary Supersoft X-ray Sources - CBSS. To check this hypothesis, we measured the time derivative of its orbital period. Observed timings of eclipse
A. S. Oliveira +13 more
core +2 more sources
, 2015 Assisted suicide is a highly controversial practice and illegal in most jurisdictions around the world, although the number of countries that have decriminalized it is increasing. Public debates as well as legislative proposals and court judgments are often confounded by a failure to carefully distinguish assisted suicide from other end-of-life ...
+4 more sources
The Anatomical Record, EarlyView.Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
wiley +1 more source
Pharmacists, Physician-Assisted Suicide, and Pain Control [PDF]
, 1999 One of the unintended consequences of the decade-old public debate about the legalization of physician-assisted suicide is an increased interest in pain control for terminally ill patients.
Meisel, Alan
core
Arthritis &Rheumatology, EarlyView.Objective Evaluate performance of the Predicting Risk of Cardiovascular Disease Events (PREVENT) calculator in rheumatoid arthritis (RA). Methods Patients with RA were matched up to 10 controls on age, sex, and enrollment year using National Veterans Health Administration, Medicare, and National Death Index data (2006–2020).
Tate M. Johnson +13 more
wiley +1 more source