Results 61 to 70 of about 8,248,213 (296)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
National assistive technology internet site
, 2002 Issued as final reportUnited States. Dept.
Bryant, Elizabeth
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Harnessing the potential of digital health for assistive technology.
Worldwide, one out of every three individuals requires assistive products to enjoy and exercise their human rights. In certain nations, only 3% have access to the assistive products they need.
Borg, Johan, +3 more
core +1 more source
Awareness and use of assistive technology among older adults with vision impairments in the Midwestern United States [PDF]
, 2003 Plan BOlder adults with vision impairments make up more than 18% of the population of the United States (Boswell, 2000; Braille Institute, 2000).
Kueffler, Mark L.
core
Determination of Teachers' Views on the Use of Assistive Technology in Special Education Classrooms
e-Kafkas Eğitim Araştırmaları DergisiThe use of assistive technologies in the education of individuals with special needs is rapidly increasing with advancements in technology, creating a greater demand for such tools in special education processes.
Serhat Odluyurt, Oğuz Özdamar
doaj +1 more source
Assistive technology and schizophrenia [PDF]
Irish Journal of Occupational Therapy, 2019 Purpose – Assistive technology (AT) has been highlighted as a tool that can support self-management for people living with schizophrenia. A gap in the literature exists regarding the views held by the stakeholders involved in the health care of an ...
Hannah Devlin +2 more
doaj +1 more source