Results 91 to 100 of about 16,010,874 (339)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
They Said: A Global Perspective on Access to Assistive Technology
Open Journal of Occupational Therapy, 2018 International experts in assistive technology from five global regions (South America, Asia Pacific, Europe, Africa, and Australia) and with affiliation to the World Health Organization (WHO) Global Cooperation on Assistive Technology (GATE) community ...
Angela K. Boisselle, Lenin C. Grajo
doaj +1 more source
Understanding Mental Ill-health as Psychosocial Disability: Implications for Assistive Technology
International ACM SIGACCESS Conference on Computers and Accessibility, 2019 Psychosocial disability involves actual or perceived impairment due to a diversity of mental, emotional, or cognitive experiences. While assistive technology for psychosocial disabilities has been understudied in communities such as ASSETS, advances in ...
Kathryn E. Ringland +5 more
semanticscholar +1 more source
, 2021 Introduction: Developing a national assistive products list is an important part of an assistive technology policy and requires knowledge of total population need, and product costs and benefits; information is not always readily available in low-income ...
Allen, Michael +12 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Awareness and use of assistive technology among older adults with vision impairments in the Midwestern United States [PDF]
, 2003 Plan BOlder adults with vision impairments make up more than 18% of the population of the United States (Boswell, 2000; Braille Institute, 2000).
Kueffler, Mark L.
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Assistive technology and schizophrenia [PDF]
Irish Journal of Occupational Therapy, 2019 Purpose – Assistive technology (AT) has been highlighted as a tool that can support self-management for people living with schizophrenia. A gap in the literature exists regarding the views held by the stakeholders involved in the health care of an ...
Hannah Devlin +2 more
doaj +1 more source
Harnessing the potential of digital health for assistive technology.
Worldwide, one out of every three individuals requires assistive products to enjoy and exercise their human rights. In certain nations, only 3% have access to the assistive products they need.
Borg, Johan, +3 more
core +1 more source