Results 51 to 60 of about 157,883 (339)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Research progress on acceptance and influencing factors of assistive technology in the elderly
Huli yanjiu, 2020 It analyzed and summarized the concept and function,as well as the current situation of acceptance among the elderly,evaluation models,tools and influencing factors of assistive technology.It was pointed out that acceptance was a key factor affecting the
JIANG Mengdie, LI Jiajia, DAI Fumin
doaj
Scientific Reports, 2023 This study investigated the effectiveness of an early aquatic exercise program on trunk muscle function and functional recovery of patients with lumbar fusion. Twenty-eight subjects were divided into two equal groups.
An-Hua Huang +4 more
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Policy and Practice Brief: Funding of Assistive Technology to Make Work a Reality [PDF]
, 2001 This brief provides a definition of assistive technology and a discussion of funding sources for assistive technology including: public schools; state vocational rehabilitation agencies; Medicaid; Medicare; and, SSA’s Plan for Achieving Self Support ...
Ronald , Ronald M +1 more
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A desirable future or unaffordable hope? Queer people becoming parents through assisted reproductive technology (ART) in Guangdong, China [PDF]
, 2022 Han Tao
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
BMC Musculoskeletal Disorders, 2019 Background Foot orthoses are widely used to manage plantar heel pain (PHP). However, the evidence concerning the effect of foot orthoses on PHP is not conclusive.
Fu-Lien Wu +4 more
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
They Said: A Global Perspective on Access to Assistive Technology
Open Journal of Occupational Therapy, 2018 International experts in assistive technology from five global regions (South America, Asia Pacific, Europe, Africa, and Australia) and with affiliation to the World Health Organization (WHO) Global Cooperation on Assistive Technology (GATE) community ...
Angela K. Boisselle, Lenin C. Grajo
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