Results 71 to 80 of about 157,883 (339)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

The mediating role of pregnancy-induced hypertension on pre-pregnancy body mass index and adverse neonatal outcomes in women with assisted reproductive technology [PDF]

, 2023
Xue Yang, Pengyu Liu, Wenqian Yu, Zhitao Zhang   +3 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Low- to High-Tech Assistive Technology for the Learning Process of Students with Special Needs in Inclusive Classrooms : A Literature Review

Ideguru
This study aims to systematically review the use of assistive technology in the learning process of students with special needs in inclusive classroom settings.
Maringgar Hangesti Putri
doaj   +1 more source

Bioengineered Textiles and Nonwovens – the convergence of bio-miniaturisation and electroactive conductive polymers for assistive healthcare, portable power and design-led wearable technology [PDF]

, 2009
Today, there is an opportunity to bring together creative design activities to exploit the responsive and adaptive ‘smart’ materials that are a result of rapid development in electro, photo active polymers or OFEDs (organic thin film electronic devices),
Oliver, Raymond, Tillotson, Jennifer, Toomey, Anne   +2 more
core   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Awareness on Assistive Technology among Pre-Service Teachers to Promote Inclusive Education

International Journal of Current Educational Studies, 2023
This research investigates the awareness of Assistive Technology among preservice teachers in the context of promoting inclusive education. A quantitative survey method was employed using a Guttman scale, validated by experts. The sample consisted of 222
Bhaskar Gurramkonda, Vanitha C.
doaj  

Inovasi Akses Assistive Technology untuk Mahasiswa Disabilitas Pendengaran dengan Pendekatan Prinsip Universal Design [PDF]

, 2017
The culture of hearing disabilities is one of the minority that is still marginalized of rights, including in this case the fulfillment of needs for access of information communication and technology (ICT).
Harahap, R. M. (Rachmita), Martokusumo, W. (Widjaja), Santosa, I. (Imam), Wahyudi, D. (Deddy)   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Towards solutions for assistive technology [PDF]

Introduction What is assistive technology? The agreed World Health Organisation definition is "Assistive technology can be defined as “any piece of equipment, or product, whether it is acquired commercially, modified, or customized, that is used to ...
National Disability Insurance Agency
core