Results 171 to 180 of about 5,206,814 (298)

The Recent Transmission and Associated Risk Factor of Mycobacterium tuberculosis in Golmud City, China

Zexuan Song,1 Wencong He,1 Xiaolong Cao,1 Aijing Ma,1 Ping He,1 Bing Zhao,1 Shengfen Wang,1 Chunfa Liu,1,2 Yanlin Zhao1 1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Center for Tuberculosis Control and
Ma A, Cao X, Zhao B, He W, Wang S, Liu C, Song Z, Zhao Y, He P   +8 more
core  

Development of a Lysine-Reactive Targeted Covalent Inhibitor for the P300/CBP-Associated Factor Bromodomain Through Structure-Based Design. [PDF]

ChemMedChem
Ede RR, Peterson KE, Begyinah RK, Tom IP, Ochoada JM, Sneddon MS, Tiu AKY, Fischer M, Shelat AA, Pomerantz WCK.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Loss of p300/CBP-associated factor aggravates cardiac remodeling via regulation of CAMKK2 acetylation. [PDF]

Exp Mol Med
Lim Y, Jeong A, Kwon DH, Lee YG, Lee YU, Cho HJ, Kee HJ, Yoon S, Yoon HG, Kim Y, Seo SB, Nam KI, Eom GH, Ahn Y, Yong J, Kim YK, Kook H.   +16 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Holistic approaches to trauma rehabilitation for forced migrants: assessing sleep as an associated factor for mental health, pain, and cardiovascular health. [PDF]

J Migr Health
Esala JJ, Lawrence S, Price CJ, Vanderminden J, Gehrz BB, Drummond S, Fonkoue IT.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway.

, 2003
A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Spence, Y, Ng, CYC, Nathwani, AC, Davidoff, AM, Zhou, J   +4 more
core  

A Semantic-Associated Factor Graph Model for LiDAR-Assisted Indoor Multipath Localization. [PDF]

Sensors (Basel)
Liu B, Han K, Deng Z, Guo G.
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source