Results 171 to 180 of about 10,769,756 (304)

Identification of the <i>wbtF</i> gene as a cytotoxicity-associated factor in <i>Francisella novicida</i> infection. [PDF]

Front Cell Infect Microbiol
Wardhana DK, Shimizu T, Watanabe K, Uda A, Watarai M.   +4 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Otubain 2 stabilizes TNF‑receptor associated factor 3 to accelerate bone fracture healing. [PDF]

Mol Med Rep
Zhang L, Guo J, Feng S, Zheng Y, Wang H, Ma H, Chen W, Zhang Y, Hou Z.   +8 more
europepmc   +1 more source

Correlation between the expressions of metastasis-associated factor-1 in colon cancer and vacuolar ATP synthase. [PDF]

World J Gastrointest Surg, 2023
He M, Cao ZF, Huang L, Zhong WJ, Xu XM, Zeng XL, Wang J.   +6 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Minimum pulse rate during sleep as a MMSE-associated factor: a multifaceted exploratory study in older adults without long-term care certification. [PDF]

BMC Geriatr
Tanaka Y, Saito K, Tsuchiya K, Iwata Y, Ando T, Mochizuki K, Taniguchi T, Mitsui T.   +7 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Insulin resistance factors associated with differentiated thyroid carcinoma and malignant cytology: serum thyroxine as an associated factor. [PDF]

Ann Med
Celescuekci LG, Pinto MP, Botelho IMB, Pavin EJ, Zantut-Wittmann DE.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Circular RNA SMARCA5 inhibits cholangiocarcinoma via microRNA-95-3p/tumor necrosis factor receptor associated factor 3 axis: Erratum. [PDF]

Anticancer Drugs
Wang G, Gao X, Sun Z, He T, Huang C, Li S, Long H.   +6 more
europepmc   +1 more source