Results 171 to 180 of about 33,523,816 (378)

Risk factors of fatigue among community-dwelling older adults in Bahir Dar, Northwest Ethiopia: a community-based cross-sectional study

Frontiers in Public Health
BackgroundFatigue is defined as subjective fatigue and a decline in physical and mental activity that does not improve with rest. Fatigue among older adults could lead to future comorbidity, mortality, decreased social interaction, greater strain on ...
Belayneh Addis Mekuria, Molla Fentanew, Yeshambel Ejigu Anteneh, Jemal Suleman, Yihalem Belet, Kefale Getie, Haimanot Melese, Fiseha Sefiwu Zinabu, Mihret Dejen Takele, Kassahun Cherkos, Assefa Gebeyehu Muluneh, Gashaw Jember Belay   +11 more
doaj   +1 more source

Prehospital identification of factors associated with death during one‐year follow‐up after acute stroke [PDF]

, 2018
Per‐Olof Hansson, Magnus Andersson Hagiwara, Peter Brink, Johan Herlitz, Birgitta Wireklint Sundström   +4 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Harmful newborn cord care practices and associated factors among mothers who gave birth in the last six months in Chencha town, Southern Ethiopia: a mixed-methods study

Frontiers in Pediatrics
BackgroundHarmful substance-related infections that cause neonatal deaths on the umbilical stump continue to be a major cause of worry, accounting for a large portion of the yearly mortality toll in developing nations such as Ethiopia.
Misgana Seifu, Sultan Hassen, Mekdim Kassa, Yosef Haile, Zeleke Girma, Temesgen Mohammed Toma, Agune Ashole, Mintesinot Melka Gujo, Wondimagegn Taye Dema, Aleme Mekuriya, Endashaw Shibru   +10 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Prevalence and associated factors of foot self-care practice among diabetic patients in Africa: systematic review and meta-analysis

Frontiers in Endocrinology
IntroductionNowadays, diabetes mellitus is a major global health issue with serious social, economic, and developmental impacts. One of its most severe complications is foot problems. Research shows that poor self-care practices in managing diabetic feet
Yibeltal Assefa Atalay, Bersufekad Wubie Alemie, Kelemu Abebe Gelaw   +2 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

The menopausal age and associated factors in Gorgan, Iran [PDF]

, 2013
Background: Considering the physical, emotional and psychological complications of early or delayed menopause on women's life, it is necessary to determine associated factors of menopause age.
Abdollahi, A.A., Ansari, A., Asayesh, H., Mansourian, M., Noroozi, M., Qorbani, M., Rezapour, A., Soleimani, M.A.   +7 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source