Results 111 to 120 of about 1,239,920 (284)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Hill's equation for a homogeneous tree

Electronic Journal of Differential Equations, 1997
The analysis of Hill's operator $-D^2 + q(x)$ for $q$ even and periodic is extended from the real line to homogeneous trees ${cal T}$. Generalizing the classical problem, a detailed analysis of Hill's equation and its related operator theory on $L^2({cal
Robert Carlson
doaj  

On The Temperature In A Non-Homogeneous Bar In Association With H--Function

, 2016
We employ the -function to obtain the formal solution of the partial differential equation: Related to a problem of heat conduction by making use of the integral and orthogonality property of Jacobi polynomials. The result generalizes a number of known particular cases on specialization of the parameters.
openaire   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Maximal Function and Riesz Transform Characterizations of Hardy Spaces Associated with Homogeneous Higher Order Elliptic Operators and Ball Quasi-Banach Function Spaces

Constructive Approximation
Let $L$ be a homogeneous divergence form higher order elliptic operator with complex bounded measurable coefficients on $\mathbb{R}^n$ and $X$ a ball quasi-Banach function space on $\mathbb{R}^n$ satisfying some mild assumptions. Denote by $H_{X,\, L}(\mathbb{R}^n)$ the Hardy space, associated with both $L$ and $X$, which is defined via the Lusin area ...
Lin, Xiaosheng, Yang, Dachun, Yang, Sibei, Yuan, Wen   +3 more
openaire   +3 more sources

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Algebras of Calderón–Zygmund Operators Associated with Para-Accretive Functions on Spaces of Normal Homogeneous Type

Mathematics
In this paper, by using several almost orthogonal estimates and a continuous Calderón reproducing formula associated with para-accretive functions, we obtain the algebras of generalized-product Calderón–Zygmund operators under the condition T1(b1)=T1*(b1)=T2(b2)=T2*(b2)=0.
Rong Liang, Taotao Zheng, Xiangxing Tao
openaire   +2 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Health Monitoring of Thick Materials Using Piezoceramic Patches, Time Signals, and Wavelet Transmittance Functions

Shock and Vibration, 2004
A relatively overlooked factor in both global and local methods of health monitoring is the nonlinear stiffness of structures caused by the cycling of cracks and delaminations.
D.R. Hughes, A. Ghoshal, E. Rowe, M.J. Sundaresan, M.J. Schulz, J.T. Feaster   +5 more
doaj   +1 more source