Results 81 to 90 of about 1,239,920 (284)

ZONEAMENTOS AMBIENTAIS: QUANDO UMA UNIDADE TERRITORIAL PODE SER CONSIDERADA HOMOGÊNEA? [PDF]

open access: yesRevista Brasileira de Cartografia, 2007
In environmental zoning territorial units are delimited that, for definition of guidelines, they are considered homogeneous. However, it is recognized that there is a variability interns not acted in map, matter to each one of them, be in the composition,
Carlos Alberto Felgueiras   +3 more
doaj  

A SHOCK LAYER ARISING AS THE SOURCE TERM COLLAPSES IN THE P(X)-LAPLACIAN EQUATION

open access: yesПроблемы анализа, 2020
We study the Cauchy–Dirichlet problem for the p(x)-Laplacian equation with a regular finite nonlinear minor term. The minor term depends on a small parameter ε > 0 and, as ε → 0, converges weakly* to the expression incorporating the Dirac delta function,
S. N. Antontsev   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Optics-based metaheuristic approach to assess critical failure surfaces in both circular and non-circular failure modes for slope stability analysis

open access: yesRock Mechanics Bulletin
In many construction projects, a proactive slope stability evaluation is a prerequisite. Although many deterministic or non-deterministic approaches have been commonly used, metaheuristic approaches have resulted in high precision and significant ...
Jayraj Singh   +4 more
doaj   +1 more source

Perubahan Fungsi Paru pada Usia Tua [Lung Function Alteration in Geriatric Patients]

open access: yesJurnal Respirasi, 2017
Aging causes many changes in biological processes characterized by progressive and widespread changes associated with increased susceptibility to various diseases. Aging is not a homogeneous process. In contrast, human organs aging at different rates are
Helmia Hasan, Rena Arusita Maranatha
doaj   +1 more source

Nonlinear Rescaling of Control Laws with Application to Stabilization in the Presence of Magnitude Saturation [PDF]

open access: yes, 1997
Motivated by some recent results on the stabilization of homogeneous systems, we present a gain-scheduling approach for the stabilization of non-linear systems.
Morin, Pascal   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

ON A NANOPHOTONIC RESPONSE DESCRIPTOR

open access: yesTASK Quarterly, 2013
The photonic response exhibited by typical semiconductor nanodevices is modeled through a notionally universal descriptor by virtue of the Green’s function associated with the generic complete, inhomogeneous differential equation. It is derived that the
EMMANUEL A. ANAGNOSTAKIS
doaj  

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