Results 1 to 10 of about 1,356,077 (312)

Impact of regulatory measures on the approval timelines of advanced therapy medicinal products by the European Medicines Agency [PDF]

open access: yesFrontiers in Medicine
IntroductionThe study examines the impact of regulatory tools, including PRIority MEdicines (PRIME) scheme, on the marketing authorization (MA) timeline of advanced therapy medicinal products (ATMPs) approved by the European Medicines Agency (EMA ...
Simonita Alaburde   +4 more
doaj   +2 more sources

On matrices associated to prime factorization of odd integers [PDF]

open access: diamondCondensed Matter Physics, 2008
In this paper we introduce in section 5 integral matrices M(n) for any factorization of an odd integer n into r distinct odd primes. The matrices appear in several versions according to a parameter ρ∈[0,1], they have size 2r×2r and their rank satisfies e.
T. Bier
doaj   +2 more sources

A novel approach to explore common prime divisor graphs and their degree based topological descriptor. [PDF]

open access: yesPLoS ONE
For the construction of a common prime divisor graph, we consider an integer [Formula: see text] with its prime factorization, where [Formula: see text] are distinct primes and [Formula: see text] are fixed positive integers. Every divisor of the integer
Ali N A Koam   +3 more
doaj   +2 more sources

Associated Prime Ideal and Minimal Prime Ideal of an Ideal of an L-Subring

open access: yesFuzzy Information and Engineering, 2023
In this paper, a systematic theory for the ideals of an L-ring L(μ,R) has been developed. Earlier the authors have introduced the concepts of prime ideals, semiprime ideals, primary ideals, and radical of an ideal in an L-ring.
Anand Swaroop Prajapati   +2 more
doaj   +1 more source

A NEW PROOF OF THE PERSISTENCE PROPERTY FOR IDEALS IN DEDEKIND RINGS AND PR¨UFER DOMAINS [PDF]

open access: yesJournal of Algebraic Systems, 2014
In this paper, by using elementary tools of commutative algebra,we prove the persistence property for two especial classes of rings. In fact, thispaper has two main sections.
Mehrdad Nasernejad
doaj   +1 more source

Ebola-GP DNA Prime rAd5-GP Boost: Influence of Prime Frequency and Prime/Boost Time Interval on the Immune Response in Non-human Primates

open access: yesFrontiers in Immunology, 2021
Heterologous prime-boost immunization regimens are a common strategy for many vaccines. DNA prime rAd5-GP boost immunization has been demonstrated to protect non-human primates against a lethal challenge of Ebola virus, a pathogen that causes fatal ...
Hadar Marcus   +10 more
doaj   +1 more source

The relationship between reversed masked priming and the tri-phasic pattern of the lateralised readiness potential. [PDF]

open access: yesPLoS ONE, 2014
One of the potential explanations for negative compatibility effects (NCE) in subliminal motor priming tasks has been perceptual prime-target interactions.
Ellen Seiss   +4 more
doaj   +1 more source

The Differential Effects of Anger and Sadness on Intertemporal Choice: An ERP Study

open access: yesFrontiers in Neuroscience, 2021
Previous research has taken a valence-based approach to examine the carryover effects of incidental emotions on intertemporal choices. However, recent studies have begun to explore the effects of specific emotions on intertemporal choices. In this study,
Tao Suo   +5 more
doaj   +1 more source

GBA-Associated Synucleinopathies: Prime Candidates for Alpha-Synuclein Targeting Compounds

open access: yesFrontiers in Cell and Developmental Biology, 2020
With disease-modifying compounds targeting alpha-synuclein available in clinical trials, patient stratification according to alpha-synuclein-specific enrichment strategies is a much-needed prerequisite.
Kathrin Brockmann, Kathrin Brockmann
doaj   +1 more source

Causal Unfoldings and Disjunctive Causes [PDF]

open access: yesLogical Methods in Computer Science, 2023
In the simplest form of event structure, a prime event structure, an event is associated with a unique causal history, its prime cause. However, it is quite common for an event to have disjunctive causes in that it can be enabled by any one of multiple ...
Marc de Visme, Glynn Winskel
doaj   +1 more source

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