Results 91 to 100 of about 1,356,077 (312)

$$U(1)_{B_3-L_2}$$ U ( 1 ) B 3 - L 2 explanation of the neutral current $$B-$$ B - anomalies

European Physical Journal C: Particles and Fields, 2021
We investigate a speculative short-distance force, proposed to explain discrepancies observed between measurements of certain neutral current decays of B hadrons and their Standard Model predictions. The force derives from a spontaneously broken, gauged $
B. C. Allanach
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Wilson-'t Hooft operators and the theta angle

, 2006
We consider $(3+1)$-dimensional $SU(N)/\mathbb Z_N$ Yang-Mills theory on a space-time with a compact spatial direction, and prove the following result: Under a continuous increase of the theta angle $\theta\to\theta+2\pi$, a 't Hooft operator $T(\gamma)$
A. Kapustin, E. Witten, F. Cachazo, M. Bianchi, Måns Henningson   +4 more
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Boundary value problems for integro-differential and singular higher-order differential equations

Open Mathematics
We investigate third-order strongly nonlinear differential equations of the type (Φ(k(t)u″(t)))′=f(t,u(t),u′(t),u″(t)),a.e. on[0,T],\left(\Phi \left(k\left(t){u}^{^{\prime\prime} }\left(t)))^{\prime} =f\left(t,u\left(t),u^{\prime} \left(t),{u}^{^{\prime ...
Anceschi Francesca, Calamai Alessandro, Marcelli Cristina, Papalini Francesca   +3 more
doaj   +1 more source

A theoretical analysis of the semileptonic decays $$\eta ^{(\prime )}\rightarrow \pi ^0l^+l^-$$ η ( ′ ) → π 0 l + l - and $$\eta ^\prime \rightarrow \eta l^+l^-$$ η ′ → η l + l -

European Physical Journal C: Particles and Fields, 2020
A complete theoretical analysis of the C- conserving semileptonic decays $$\eta ^{(\prime )}\rightarrow \pi ^0l^+l^-$$ η ( ′ ) → π 0 l + l - and $$\eta ^\prime \rightarrow \eta l^+l^-$$ η ′ → η l + l - ( $$l=e$$ l = e or $$\mu $$ μ ) is carried out ...
Rafel Escribano, Emilio Royo
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Powers of edge ideals

Le Matematiche, 2012
We compute the Betti numbers for all the powers of initial and final lexsegment edge ideals. For the powers of the edge ideal of an anti–d−path, we prove that they have linear quotients and we characterize the normally torsion–free ideals. We determine a
Carmela Ferrò, Mariella Murgia, Oana Stefania Olteanu   +2 more
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