Results 131 to 140 of about 1,422,825 (312)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A novel approach to explore common prime divisor graphs and their degree based topological descriptor.

PLoS ONE
For the construction of a common prime divisor graph, we consider an integer [Formula: see text] with its prime factorization, where [Formula: see text] are distinct primes and [Formula: see text] are fixed positive integers. Every divisor of the integer
Ali N A Koam, Azeem Haider, Ali Ahmad, Moin Akhtar Ansari   +3 more
doaj   +1 more source

Food-Associated Stress Primes Foodborne Pathogens for the Gastrointestinal Phase of Infection [PDF]

, 2018
Nathan Horn, Arun K. Bhunia
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

On the associated primes and the depth of the second power of squarefree monomial ideals [PDF]

, 2013
Naoki Terai, Ngô Viêt Trung
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The Puzzling Long GRB 191019A: Evidence for Kilonova Light

The Astrophysical Journal
GRB 191019A was a long gamma-ray burst (GRB) lasting ~65 s and, as such, originally thought to be linked to a core-collapse supernova. However, even though follow-up observations identified the optical counterpart close to the bright nucleus of a nearby ...
G. Stratta, A. M. Nicuesa Guelbenzu, S. Klose, A. Rossi, P. Singh, E. Palazzi, C. Guidorzi, A. Camisasca, S. Bernuzzi, A. Rau, M. Bulla, F. Ragosta, E. Maiorano, D. Paris   +13 more
doaj   +1 more source

IFN-γ Primes Intact Human Coronary Arteries and Cultured Coronary Smooth Muscle Cells to Double-Stranded RNA- and Self-RNA–Induced Inflammatory Responses by Upregulating TLR3 and Melanoma Differentiation-Associated Gene 5 [PDF]

, 2010
Usman Ahmad, Rahmat Ali, Amir H. Lebastchi, Lingfeng Qin, Sheng-fu L. Lo, Alexander O. Yakimov, Salman Khan, Jonathan C. Choy, Arnar Geirsson, Jordan S. Pober, George Tellides   +10 more
openalex   +1 more source

Vojta's conjecture, heights associated with subschemes, and primitive prime divisors in arithmetic dynamics [PDF]

, 2020
Yohsuke Matsuzawa
openalex   +1 more source