PRIME: an interpretable artificial intelligence model based on liquid biopsy improves prediction of progression risk in non-small cell lung cancer. [PDF]
Wang Y +9 more
europepmc +1 more source
On Energy of Prime Ideal Graph of A Commutative Ring Associated with Seidel-Based Matrices
Mamika Ujianita Romdhini
openalex +2 more sources
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Congruency effects can interact even when controlling for the reactivation aversion effect: implications for the generality-specificity paradox in hybrid distractor-interference tasks. [PDF]
Dunaway MG, Weissman DH.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Anchor objects guide spatial attention during visual search. [PDF]
Souza-Wiggins M, Geng JJ.
europepmc +1 more source
Primes in Sequences Associated to Polynomials (After Lehmer) [PDF]
Manfred Einsiedler +2 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Periodontitis and incident cognitive decline and dementia: A 15-year prospective cohort study of older men residing in Northern Ireland. [PDF]
Farsi DN +13 more
europepmc +1 more source

