Results 261 to 270 of about 261,920 (288)

Targeting inflammasomes as a therapeutic potential for HIV/AIDS. [PDF]

open access: yesCell Mol Life Sci
Zhang H   +5 more
europepmc   +1 more source

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad   +8 more
wiley   +1 more source

TIRE-seq simplifies transcriptomics via integrated RNA capture and library preparation. [PDF]

open access: yesSci Rep
O'Keeffe P   +22 more
europepmc   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont   +4 more
wiley   +1 more source

Heterologous prime-boost immunization combining parenteral and mucosal routes with different adjuvants mounts long-lived CD4+ T cell responses in lungs. [PDF]

open access: yesFront Immunol
Kavishna R   +8 more
europepmc   +1 more source

Immunopeptidomics identified antigens for mRNA-lipid nanoparticle vaccines with alpha-galactosylceramide in multiple myeloma therapy. [PDF]

open access: yesJ Immunother Cancer
Van der Vreken A   +15 more
europepmc   +1 more source

Optimised genome editing for precise DNA insertion and substitution using Prime Editors in zebrafish

open access: yes
Ono Y   +10 more
europepmc   +1 more source

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