Results 81 to 90 of about 1,422,825 (312)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

On Prime Rings with Derivations

open access: yesAxioms
This paper identifies all derivations associated with two well-known non-commutative prime rings and provides some remarks on one of these derivations, called the prime derivation.
Khalid H. Al-Shaalan
doaj   +1 more source

Observing ageism implicitly using the numerical parity judgment task

open access: yesScientific Reports, 2023
Objective magnitude representations may be prone to subjective percepts when judging human beings. An elderly man is clearly “large” in terms of age. But, is he truly perceived as “big” in our minds?
D. Aisenberg-Shafran   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

On Binomial Ideals associated to Linear Codes [PDF]

open access: yes, 2014
Recently, it was shown that a binary linear code can be associated to a binomial ideal given as the sum of a toric ideal and a non-prime ideal. Since then two different generalizations have been provided which coincide for the binary case. In this paper,
Dück, N., Zimmermann, K. -H.
core  

ON THE ASSOCIATED PRIMES OF LOCAL COHOMOLOGY [PDF]

open access: yesNagoya Mathematical Journal, 2018
Let $R$ be a commutative Noetherian ring of prime characteristic $p$. In this paper, we give a short proof using filter regular sequences that the set of associated prime ideals of $H_{I}^{t}(R)$ is finite for any ideal $I$ and for any $t\geqslant 0$ when $R$ has finite $F$-representation type or finite singular locus. This extends a previous result by
Dao, Hailong, Quy, Pham Hung
openaire   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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