Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Bulletin of the Rubber Growers' Association (Incorporated). Vol. 14, no. 6 (June, 1932)
, 2014 Journal, covering all subjects related to the rubber plantation industry, published by the Rubber Growers' Association from 1919 ...
Rubber Growers' Association
core
Multidisciplinary experts consensus for assessment and management of vestibular migraine
Chinese Medical Journal, 2019 Stroke and Vertigo Association of Chinese Stroke Association +1 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Bulletin of the Rubber Growers' Association (Incorporated). Vol. 16, no. 9 (September, 1934)
, 2014 Journal, covering all subjects related to the rubber plantation industry, published by the Rubber Growers' Association from 1919 ...
Rubber Growers' Association
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Bulletin of the Rubber Growers' Association (Incorporated). Vol. 16, no. 11 (November, 1934)
, 2014 Journal, covering all subjects related to the rubber plantation industry, published by the Rubber Growers' Association from 1919 ...
Rubber Growers' Association
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Bulletin of the Rubber Growers' Association (Incorporated). Vol. 18, no. 10 (October, 1936)
, 2014 Journal, covering all subjects related to the rubber plantation industry, published by the Rubber Growers' Association from 1919 ...
Rubber Growers' Association
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source