Results 251 to 260 of about 13,598,149 (296)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Thyroid dysfunction and its association with dyslipidaemia and dysglycaemia in adults: a cross-sectional study of primary-care laboratory records (2019-2025). [PDF]

BMJ Open
Doğan Tiryaki H, Erdoğan K, Kurt O, Şeker N, Küçükkelepçe O.   +4 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Salivary Versus Circulating Insulin in Humans: Quantitative Evidence and Validation Requirements. [PDF]

Biomolecules
Albanese L.
europepmc   +1 more source

Association of atherogenic index of plasma with gestational diabetes mellitus and birth weight outcomes, and the mediating role of blood glucose. [PDF]

J Diabetes Investig
Zhao D, Song Y, Li N, Zhang Y, Li Y, Wang K, Mi Y, Shang L, Qu P.   +8 more
europepmc   +1 more source

Exploring the association between low birth weight and different forms of child malnutrition: A multi-country propensity score matching analysis in South Asia. [PDF]

PLoS One
Hussain MP, Rahman MM, Kader MR, Talukder MRI, Khan MTF, Ahmmed F.   +5 more
europepmc   +1 more source

Reliability-Aware Semantic Gating with Retrieval-Augmented Association for Online Multi-Object Tracking Under Industrial Low-Altitude Proxy Conditions. [PDF]

J Imaging
Guo R, He Y.
europepmc   +1 more source

Intramuscular Fat Infiltration and Knee Osteoarthritis: A Systematic Review and Meta-Analysis. [PDF]

Physiother Res Int
Yu L, Chen C, Zhang G, Huang Q, Ye M, Makihara Y, Nishida Y.   +6 more
europepmc   +1 more source