Results 241 to 250 of about 10,380,714 (314)

Hypertension Among Medical Students in Lubumbashi, Democratic Republic of the Congo: Prevalence, Associated Factors and Comparison of the 2025 ACC/AHA and JNC 7 Classifications. [PDF]

Int J Hypertens
Musung JM, Muyumba EK, Katchunga PB, Kakoma PK, Isango YI, Bugeme M, Kamalo BMK, Ngungwa OM, Kapya HK, Malamba DL, Mukuku O.   +10 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Conditional validity in LLM-mediated L2 assessment: an argument-based systematic review and meta-analysis. [PDF]

Front Res Metr Anal
Alghamdi LH, Alghizzi TM.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Agreement on implementation of article VII of the General Agreement on Tariffs and Trade and protocol

, 1979
General Agreement on Tariffs and Trade (Körperschaft)
core  

Visual Acuity: Comparison of ETDRS Charts Using Latin Letters, Tumbling E, or Landolt C Optotypes. [PDF]

Invest Ophthalmol Vis Sci
Kalloniatis M, Wang H, Meier K, Patel NB, Phu J.   +4 more
europepmc   +1 more source

Pleural plaques and interstitial lung abnormalities in AGES-Reykjavik study. [PDF]

ERJ Open Res
Ko Y, Gudmundsson G, Fukuda T, Nakamura Y, Bjarnadottir H, Gudmundsdottir V, Nishino M, Gudnason V, Hunninghake GM, Hatabu H.   +9 more
europepmc   +1 more source

Agreement and Reliability of a Newly Developed Tidal Volume Monitoring Device in Bag-Valve Ventilation and Intubation Scenarios: A Simulation-Based Study. [PDF]

Bioengineering (Basel)
Lee Y, Lee EY, Lee HY.
europepmc   +1 more source

Comparison of Sizing Methods to Optimize Device Selection for Percutaneous Closure of Atrial Septal Defects. [PDF]

Cardiol Res Pract
Vural Ç, Baykan A, Doğan A, Kum YE, Akay ÖP, Üzüm K, Narin N.   +6 more
europepmc   +1 more source

MRI-Derived Scapular Superomedial Angle and Acromial Morphology: A Retrospective Cross-Sectional Reliability and Morphometric Association Study. [PDF]

J Clin Med
Kandefer S, Gür V, Gökgöz MB, Can MA, Taş M, Memiş KB, Kantarcı M, Koçkara N, Yapıcı F.   +8 more
europepmc   +1 more source