Disease model distortion in association studies [PDF]
Genetic Epidemiology, 2011 AbstractMost findings from genome‐wide association studies (GWAS) are consistent with a simple disease model at a single nucleotide polymorphism, in which each additional copy of the risk allele increases risk by the same multiplicative factor, in contrast to dominance or interaction effects.
Vukcevic, D +3 more
openaire +4 more sources
Meta-analysis for genome-wide association studies using case-control design: application and practice [PDF]
Epidemiology and Health, 2016 This review aimed to arrange the process of a systematic review of genome-wide association studies in order to practice and apply a genome-wide meta-analysis (GWMA).
Sungryul Shim +4 more
doaj +1 more source
Exploration in Free Word Association Networks: Models and Experiment
, 2013 Free association is a task that requires a subject to express the first word to come to their mind when presented with a certain cue. It is a task which can be used to expose the basic mechanisms by which humans connect memories.
Behzad, M. Djalali +2 more
core +1 more source
Types of dependence and time-dependent association between two lifetimes in single parameter copula models [PDF]
, 2006 Most publications on modeling insurance contracts on two lives, assuming dependence of the two lifetimes involved, focus on the time of inception of the contract.
Spreeuw, J.
core +1 more source
A novel computational strategy for DNA methylation imputation using mixture regression model (MRM)
BMC Bioinformatics, 2020 Background DNA methylation is an important heritable epigenetic mark that plays a crucial role in transcriptional regulation and the pathogenesis of various human disorders.
Fangtang Yu +3 more
doaj +1 more source
Long Gamma-Ray Burst Progenitors: Boundary Conditions and Binary Models [PDF]
, 2007 The observed association of Long Gamma-Ray Bursts (LGRBs) with peculiar Type Ic supernovae gives support to Woosley`s collapsar/hypernova model, in which the GRB is produced by the collapse of the rapidly rotating core of a massive star to a black hole ...
Heuvel, E. P. J. van den, Yoon, S. -C.
core +1 more source
Heatmaps for Patterns of Association in log-Linear Models
Socius, 2020 Log-linear models offer a detailed characterization of the association between categorical variables, but the breadth of their outputs is difficult to grasp because of the large number of parameters these models entail.
Mauricio Bucca
doaj +1 more source
Egyptian Journal of Medical Human Genetics, 2021 Background Behcet’s disease (BD) is a systemic inflammatory disease of the blood vessels and affects various body parts. This study aimed to determine the association of four single-nucleotide polymorphisms (SNPs) and BD in the Egyptian population using ...
Mohamed M. Emara +5 more
doaj +1 more source
Asymptotic inference for semiparametric association models
, 2009 Association models for a pair of random elements $X$ and $Y$ (e.g., vectors) are considered which specify the odds ratio function up to an unknown parameter $\bolds\theta$.
Osius, Gerhard
core +1 more source
Associations between blood glucose and carotid intima-media thickness disappear after adjustment for shared risk factors: the KORA F4 study. [PDF]
, 2012 The association between blood glucose and carotid intima-media thickness (CIMT) is considered to be established knowledge. We aimed to assess whether associations between different measures of glycaemia and CIMT are actually independent of anthropometric
Ebert, Nina +7 more
core +4 more sources