Results 131 to 140 of about 1,906,656 (324)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Strobili Development in Western White Pine: Periodicity, Prediction, and Association with Weather [PDF]

, 1971
Gerald E. Rehfeldt, Albert R. Stage, R. T. Bingham   +2 more
openalex   +1 more source

Genome-Wide Association and Genomic Prediction for Fry Color in Potato [PDF]

, 2020
Stephen Byrne, Fergus Meade, Francesca Mesiti, Denis Griffin, Colum Kennedy, Dan Milbourne   +5 more
openalex   +1 more source

Light Stop Searches at the LHC in Events with two b-Jets and Missing Energy

, 2010
We propose a new method to discover light top squarks (stops) in the co-annihilation region at the Large Hadron Collider (LHC). The bino-like neutralino is the lightest supersymmetric particle (LSP) and the lighter stop is the next-to-LSP. Such scenarios
A. D. Sakharov, A. D. Sakharov, A. D. Sakharov, J. S. Kim, M. Drees, S. Bornhauser, S. Grab, S. P. Martin   +7 more
core   +1 more source

EGBMMDA: Extreme Gradient Boosting Machine for MiRNA-Disease Association prediction

Cell Death and Disease, 2018
Associations between microRNAs (miRNAs) and human diseases have been identified by increasing studies and discovering new ones is an ongoing process in medical laboratories.
Xing Chen, Li Huang, Di Xie, Qi Zhao
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Hierarchical graph attention network for miRNA-disease association prediction.

Molecular Therapy, 2022
Zhengwei Li, Tangbo Zhong, Deshuang Huang, Zhuhong You, Ru Nie   +4 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Top quark forward-backward asymmetry and W^prime bosons

, 2012
The top quark forward-backward asymmetry measured at the Fermilab Tevatron collider deviates from the standard model prediction. A W^prime boson model is described, where the coupling W^prime-t-d is fixed by the tt_bar forward-backward asymmetry and ...
C. Delaunay, Daniel Duffty, Hao Zhang, Zack Sullivan   +3 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source