Results 131 to 140 of about 8,357,963 (324)

Recent activities of IAG working group “Ionosphere Prediction” [PDF]

open access: yes, 2018
Ionospheric disturbances pose, for instance, an increasing risk on economy, national security, satellite and airline operations, communications networks and the navigation systems.
Berdermann, Jens   +8 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Simple model for sequence prediction based on dendritic spatiotemporal integration

open access: yesSistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2018
Recent experiments on dendritic spatiotemporal integration reveal the much bigger computational potential of a single neuron. An individual dendritic branch can work as a coincidence detector due to a dendritic spike initiated with locally spatially and ...
Viacheslav M. Osaulenko
doaj   +1 more source

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection [PDF]

open access: yes, 2018
Previous studies have detected a higher level of ferritin in patients with hepatocellular carcinoma (HCC), but a potential causal association between serum ferritin level and hepatocarcinogenesis remains to be clarified.
Bian, Zhenyuan   +8 more
core   +1 more source

Learning Social Relation Traits from Face Images

open access: yes, 2015
Social relation defines the association, e.g, warm, friendliness, and dominance, between two or more people. Motivated by psychological studies, we investigate if such fine-grained and high-level relation traits can be characterised and quantified from ...
Loy, Chen Change   +3 more
core   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Light Stop Searches at the LHC in Events with two b-Jets and Missing Energy

open access: yes, 2010
We propose a new method to discover light top squarks (stops) in the co-annihilation region at the Large Hadron Collider (LHC). The bino-like neutralino is the lightest supersymmetric particle (LSP) and the lighter stop is the next-to-LSP. Such scenarios
A. D. Sakharov   +7 more
core   +1 more source

Hierarchical graph attention network for miRNA-disease association prediction.

open access: yesMolecular Therapy, 2022
Zhengwei Li   +4 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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