Results 201 to 210 of about 1,960,778 (332)

A Gene-disease Association Prediction Algorithm Based on Multi-source Data Fusion

, 2022
Fei Wang
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Integrating multiple microRNA functional similarity networks for improved disease-microRNA association prediction. [PDF]

Biol Methods Protoc
Le DH.
europepmc   +1 more source

Association of Known Loci With Lipid Levels Among Children and Prediction of Dyslipidemia in Adults [PDF]

, 2011
Emmi Tikkanen, Tarja Tuovinen, Elisabeth Widén, Terho Lehtimäki, Jorma Viikari, Mika Kähönen, Leena Peltonen, Olli T. Raitakari, Samuli Ripatti   +8 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

MHCLMDA: multihypergraph contrastive learning for miRNA-disease association prediction. [PDF]

Brief Bioinform, 2023
Peng W, He Z, Dai W, Lan W.
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

MRDDA: a multi-relational graph neural network for drug-disease association prediction. [PDF]

J Transl Med
Chen C, Zhou Y, Li Y, Xu J, Li D, Wang L.   +5 more
europepmc   +1 more source

Supplementary Figure S6 from Association and prediction utilizing craniocaudal and mediolateral oblique view digital mammography and long-term breast cancer risk

Simin Chen, Rulla M. Tamimi, Graham A. Colditz, Shu Jiang   +3 more
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source