Results 291 to 300 of about 1,960,778 (332)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

HHOMR: a hybrid high-order moment residual model for miRNA-disease association prediction. [PDF]

Brief Bioinform
Li Z, Wan L, Wang L, Wang W, Nie R.
europepmc   +1 more source

The association of Whole and Segmental Body Composition and Anaerobic Performance in Crossfit® athletes: sex differences and performance prediction

Tomás Ponce-García, Jerónimo García-Romero, Laura Carrasco-Fernández, Alejandro Castillo-Domínguez, Javier Benítez‐Porres   +4 more
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Global-local aware Heterogeneous Graph Contrastive Learning for multifaceted association prediction in miRNA-gene-disease networks. [PDF]

Brief Bioinform
Si Y, Huang Z, Fang Z, Yuan Z, Huang Z, Li Y, Wei Y, Wu F, Yao YF.   +8 more
europepmc   +1 more source

A method for miRNA diffusion association prediction using machine learning decoding of multi-level heterogeneous graph Transformer encoded representations. [PDF]

Sci Rep
Wen S, Liu Y, Yang G, Chen W, Wu H, Zhu X, Wang Y.   +6 more
europepmc   +1 more source

SCPLPA: An miRNA-disease association prediction model based on spatial consistency projection and label propagation algorithm. [PDF]

J Cell Mol Med
Chen M, Deng Y, Li Z, Ye Y, Zeng L, He Z, Peng G.   +6 more
europepmc   +1 more source

Three-layer heterogeneous network based on the integration of CircRNA information for MiRNA-disease association prediction. [PDF]

PeerJ Comput Sci
Qu J, Liu S, Li H, Zhou J, Bian Z, Song Z, Jiang Z.   +6 more
europepmc   +1 more source

Author Correction: A method for miRNA-disease association prediction using machine learning decoding of multi-layer heterogeneous graph Transformer encoded representations. [PDF]

Sci Rep
Wen S, Liu Y, Yang G, Chen W, Wu H, Zhu X, Wang Y.   +6 more
europepmc   +1 more source