Results 91 to 100 of about 2,360,798 (281)

Privacy Preserving Association Rule Mining: Taxonomy, Techniques, and Metrics

open access: yesIEEE Access, 2019
In the last decades, pervasive computing is generating a growing quantity of data. Data mining (DM) technology has become increasingly popular.
Lili Zhang, Wenjie Wang, Yuqing Zhang
doaj   +1 more source

A statistical development of fixed odds betting rules in soccer [PDF]

open access: yes
Two simple but seemingly profitable betting rules for betting on the away win in association football are developed. One rule is consistent with avoiding those games in which there is a clear favourite.
Don Webber, Ian Milliner, Paul White
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Risk Evolution Analysis of Seafarers’ Unsafe Acts in Maritime Accidents Based on Directed Weighted CN

open access: yesApplied Sciences
Seafarers’ unsafe acts as the direct causes of maritime accidents are considered to be the result of the interaction between complex and dynamic influencing factors.
He Lan, Xiaoxue Ma
doaj   +1 more source

Association rule mining approach: evaluating pre-purchase risk intentions in the online second-hand goods market

open access: yesOeconomia Copernicana, 2019
Research background: A considerable amount of research has been conducted on the riskiness associated with online transactions in general. However, few studies have paid particular attention to the risk of online second-hand goods transactions.
Abdul Bashiru Jibril   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Safety of combined drug use in patients with cardiovascular and cerebrovascular diseases: an analysis based on the spontaneous reporting database of adverse drug reactions in Hubei Province

open access: yesFrontiers in Pharmacology
ObjectiveThere is a lack of studies investigating the safety of combination regimens specifically for cardiovascular and cerebrovascular diseases.
Jia Wang   +3 more
doaj   +1 more source

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