Results 81 to 90 of about 6,573,619 (301)

Identification of Performer of Text by Frequency Grammatical Features and Syntactical Singularities

open access: yesБезопасность информационных технологий, 2011
The approach is suggested to the identification of a performer of texts by analysis of frequency of grammatical and syntactic features of the text. The approach is applicable when there are some texts of known performer and the performer of some other ...
S. D. Kulik   +2 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Using Association Rules for the Detection of Risk Factors in Gastric Cancer

open access: yesمجله انفورماتیک سلامت و زیست پزشکی, 2015
Introduction: Gastric cancer is the second cause of death from cancer after lung cancer in the world It`s incidence is varied in different regions of the words.
Seyed Abbas Mahmoodi   +2 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Data on coding association rules from an inpatient administrative health data coded by International classification of disease - 10th revision (ICD-10) codes

open access: yesData in Brief, 2018
Data presented in this article relates to the research article entitled “Exploration of association rule mining for coding consistency and completeness assessment in inpatient administrative health data” (Peng et al.
Mingkai Peng   +6 more
doaj   +1 more source

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