Results 211 to 220 of about 333,700 (261)

Ecological influences on host-parasite dynamics among <i>Biomphalaria</i> snails in two schistosomiasis endemic regions of Kenya. [PDF]

open access: yesFront Parasitol
Parsimei FN   +7 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Benefits, challenges, and the way forward: medical specialists' perception on family physician integration in healthcare system in Tanzania. [PDF]

open access: yesBMC Prim Care
Anselm J   +8 more
europepmc   +1 more source

Dynamic chiral quenching of europium and terbium excited states.

open access: yesPhys Chem Chem Phys
Wen X   +4 more
europepmc   +1 more source

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