Results 121 to 130 of about 5,566 (293)
Beyond Prometheus: Creativity, discourse, ideology and the Anthropocene [PDF]
, 2018 This article considers the strange confluence of the rhetoric of creativity and commerce at key points across the “Great Acceleration”. It argues that although the idea of creativity has its most common contemporary expression in art, it does not in fact
Nelson, Camilla
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
New models for learning flexibility: negotiated choices for both academics and students [PDF]
, 2007 ‘Flexible learning’ represents a need associated with ‘lifelong learning’ and the equipping of graduates to actively engage in a ‘knowledge society’. While the precise meaning of each of these terms is not easy to discern, notions of flexible learning ...
McDonald, Jacquelin, Nagy, Judy
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Proposal of an interpretative theoretical frame about sport associationism in Spain
European Journal of Human Movement, 2010 The article is a theoretical essay about sport organisations in Spain. It has two parts. The first one deals with the heterogeneity of sport organisations. This is analized from an historical and present perspective.
N. Puig, A. Moreno, C. López
doaj
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
An Approach on Integrated Territorial Competitiveness to Ensure Long Term Viability in Rural Areas of Andalusia (Spain) [PDF]
After more than ten years of rural development programmes in Andalusia, there is ongoing concern about the sustainability of the rural development initiated by the LEADER-PRODER programmes in the hypothetical event that such programmes were no longer in ...
Cobos, Rosa Gallardo +2 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
L'Origen de la formació d'adults a Catalunya (1874-1936) : l'associacionisme com a trama educativa = The origin of adult teaching in Catalunya (1874-1936) : associationism as an educational network [PDF]
, 2010 El text proposa un exercici històric circumscrit en el moviment associatiu popular català, variat i complex, entre 1874 i 1936. Dinàmica cultural que fonamenta i origina una primera trama educativa del que avui anomenem formació d'adults.The text ...
Rodríguez i Bosch, Josep Lluís
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source