Results 181 to 190 of about 5,566 (293)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

How people learn: insights for medical faculty. [PDF]

Proc (Bayl Univ Med Cent)
Cox T, Columbus C, Higginbotham J, Ahmed K.   +3 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

A Tale of Two Comparative Psychologies: Reply to Commentaries. [PDF]

J Comp Psychol, 2014
Smith JD, Couchman JJ, Beran MJ.
europepmc   +1 more source

An intentional basis for corporate personality - RETRACTION [PDF]

, 2012
Anthony Amatrudo, Cole, Dworkin, Dworkin, Elster, Gilbert, Hume, Hume, Hurley, Korsgaard, Lewis, McClennen, Parfit, Rawls, Rawls, Rawls, Raz, Searle, Searle, Sugden, Vellerman   +20 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Challenging large language models' "intelligence" with human tools: A neuropsychological investigation in Italian language on prefrontal functioning. [PDF]

Heliyon
Loconte R, Orrù G, Tribastone M, Pietrini P, Sartori G.   +4 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Generators of Inequality and Inequity Affecting Dental Patient Safety: A Grounded Theory Approach. [PDF]

Int J Environ Res Public Health
Gil-Alzate DA, Posada-Zapata IC, Agudelo-Suárez AA.   +2 more
europepmc   +1 more source

After 150 years of watching: is there a need for synthetic ethology? [PDF]

Anim Cogn, 2023
Abdai J, Miklósi Á.
europepmc   +1 more source