The Gut-Disc Axis: Mendelian Randomization Study Reveals Causal Effects of Gut Microbiota on Intervertebral Disc Degeneration Not Mediated by Systemic Inflammation. [PDF]
Yan Z +6 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
AGENTS OF TRUST: BUSINESS ASSOCIATIONS IN AGRI-FOOD SUPPLY SYSTEMS
The generation of trust between business partners is a strategic issue for firms in competitive agri-food markets. It is asserted that business associations can be important facilitators of trust between firms.
Rademakers, Martijn F.L.
core
Dementia risk by metabolic health and obesity in two prospective cohorts. [PDF]
Nakash M +6 more
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Aberrant CD4 expression in plasmablastic transformation of multiple myeloma
Kohei Shiroshita +5 more
doaj +1 more source
Role of professional associations in the drive for policy change and uptake of new WHO recommendations for the prevention and treatment of postpartum hemorrhage. [PDF]
Wamae R +4 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Persistent maternal mental health and child's behavioural, academic, and educational outcomes: evidence from national longitudinal study. [PDF]
Seema M, Afoakwah C, Byrnes J.
europepmc +1 more source

