Results 141 to 150 of about 16,405,289 (331)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Educational Associative Dictionary as a Method of Creating of Language

open access: yesФилологический класс, 2013
The paper considers a new type of manuals – an educational associative dictionary. The author postulates the necessity of learning the associative norms in the lexicography.
doaj  

Interpretative Potential of Abstract and Concrete Common Nouns

open access: yesСибСкрипт
The article describes the interpretative potential of abstract and concrete common nouns. In interpretational linguistics, any word may become part of dialogue, which means that its semantics is not static.
E Yu. Pozdnyakova, N. N. Shpilnaya
doaj   +1 more source

Associative learning in baboons and humans: Species differences in learned attention to visual features [PDF]

open access: yes, 1998
We examined attention shifting in baboons and humans during the learning of visual categories. Within a conditional matching-to-sample task, participants of the two species sequentially learned two two-feature categories which shared a common feature ...
Fagot, J, Kruschke, J K, Vauclair, J
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Experiments With Sequential Associative Memories

open access: yes, 1988
Humans are very good at manipulating sequential information, but sequences present special problems for connectionist models.As an approach to sequential problems we have examined totally connected subnetworks of cells called sequential associative memories (SAM's).
Gallant, Stephen I., King, Donna J.
openaire   +3 more sources

THE EXPERIENCE OF USING ASSOCIATION EXPERIMENT DATA IN STUDYING A FRAGMENT OF THE LINGUISTIC PICTURE OF THE WORLD

open access: yesВестник Кемеровского государственного университета, 2015
The purpose of this work is the construction of the associative field of the concepts TOP/BOTTOM as the objects of designing the liguistic picture of the world in the Chinese and Russian languages, and also the description of the associates included in ...
N. A. Kozlova
doaj  

Semantic Gestalt of the Associative Field of the Concept LAND of Speakers of Russian and Chinese Linguocultures Based on the Data of Free Associative Experiment

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
The construction of the semantic gestalt of the associative field of the concept LAND in Russian and Chinese speakers using the results of the associative experiment is an actual problem.
Irina I. Mitrofanova   +2 more
doaj   +1 more source

Representing Images' Meanings by Associative Values with Given Lexicons Considering the Semantic Tolerance Relation

open access: yesAdvances in Multimedia, 2011
An approach of representing meanings of images based on associative values with lexicons is proposed. For this, the semantic tolerance relation model (STRM) that reflects the tolerance degree between defined lexicons is generated, and two factors of ...
Ying Dai
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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