Results 81 to 90 of about 19,178,138 (322)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Interpretative Potential of Abstract and Concrete Common Nouns
СибСкриптThe article describes the interpretative potential of abstract and concrete common nouns. In interpretational linguistics, any word may become part of dialogue, which means that its semantics is not static.
E Yu. Pozdnyakova, N. N. Shpilnaya
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Modeling the Evolution of Dynamic Brain Processes During an Associative Learning Experiment
, 2016 We develop a new time series model to investigate the dynamic interactions between the nucleus accumbens and the hippocampus during an associative learning experiment.
M. Fiecas, H. Ombao
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Value Component of American Language Group Consciousness
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2017 The article presents the results of a free associative experiment. The purpose of the experiment was to determine the categorical components of the value system of the American ethnic group at the present stage.
Larisa O. Butakova +1 more
doaj +1 more source
Vigabatrin associated visual field constriction [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1999 Peripheral visual field defects in patients taking vigabatrin seem to arise in a proportion of patients. Typically a concentric narrowing of the field is seen with preservation of central acuity and colour vision. Case definition remains poorly defined and prevalence figures ranging from as low as 0.14% to as high as 39% have appeared.1 2 The high ...
openaire +1 more source
Journal of Neuroscience, 2006 The anterior cingulate and orbital cortices and the ventral striatum process different aspects of reward evaluation, whereas the dorsolateral prefrontal cortex and the dorsal striatum are involved in cognitive function.
S. Haber +3 more
semanticscholar +1 more source