Results 11 to 20 of about 53,813 (260)

Effective therapeutic targeting of CTNNB1-mutant hepatoblastoma with WNTinib. [PDF]

Mol Oncol
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Balaseviciute U, Huguet-Pradell J, Abril-Fornaguera J, Gris-Oliver A, Rialdi A, Fernández-Martínez E, Montironi C, Del Pozo V, Houghton P, Zanatto L, Mesropian A, Keraite I, Thung S, Armengol C, Sancho-Bru P, Guccione E, Pinyol R, Llovet JM.   +17 more
europepmc   +2 more sources

Patients' Associations as Co-Creators of Knowledge: Insights From a Community-Based Participatory Research Study (ProSafe Project). [PDF]

Health Sci Rep
ABSTRACT Background and Aims Patient and public involvement and engagement (PPIE) in research is crucial for producing knowledge that is meaningful to the participating community. Sharing PPIE principles into practical tools and strategies enriches the development of participatory research methodologies.
Moretti F, Colpo S, Montresor S, Facchinello D, Robello R, Mazzi M, Tardivo S, Stagi L, Stefano L, Zotti A, Ambroso L, Destro C, Leone S, Petruzzelli D, Moretti U, Rimondini M.   +15 more
europepmc   +2 more sources

Management of the Acute Coronary Syndrome patient [PDF]

Global & Regional Health Technology Assessment, 2022
Giovanni Esposito, Fabrizio Ricci, Giovanni Battista Zito   +2 more
doaj   +2 more sources

Un viaggio verticale

Ticontre: Teoria Testo Traduzione, 2022
In questo studio si vuole proporre  un’analisi della figuralità del mare nella vita e nell’opera di Elsa Morante, a partire dalle associazioni linguistiche legate allo spazio marino. L’indagine esplorerà sia la relazione semantica della parola con altri
Lucia Faienza
doaj   +1 more source

Bilancio Integrato Arcigay 2021

European Journal of Volunteering and Community-Based Projects, 2022
Per il secondo anno, Arcigay ha volontariamente deciso di pubblicare il proprio Report Integrato al fine di illustrare a tutti gli attori coinvolti l’impegno profuso nella creazione di attività in grado di generare valore in senso ampio, non solo per la
Paolo Biancone, Silvana Secinaro, Valerio Brescia, Davide Calandra, Federica Bassano, Matteo Cavalieri, Piazzoni Gabriele, Fabrizio Sorbara, Ariberto Vergnani   +8 more
doaj   +2 more sources

Patient Reported Outcomes from research to clinical practice. Opportunities and future challenges

AboutOpen, 2023
PROs, highly considered tools for the personalization of therapies and for research, are still scarcely used in clinical practice. Patient organizations played an important role in the validation process of these tools and are engaged in their ...
Elisabetta Iannelli
doaj   +1 more source

Trefoil Factor-3 Is a Hypoxia-Triggered Pro-Tumorigenic Factor in Hepatoblastoma. [PDF]

Liver Int
ABSTRACT Background & Aims Hepatoblastoma (HB) is the most common malignant liver tumour in children. Despite improved survival in low‐risk disease, outcomes for advanced or relapsed HB remain poor, emphasising the need for new therapeutic targets.
Martínez-Pérez LA, Latasa MU, Uriarte I, López-Pascual A, Elurbide J, Strnad P, Frankova S, Sticova E, Fabian O, Arechederra M, Santamaria E, Argemi J, Sangro B, Foglia B, Parola M, Gutiérrez-Angulo M, Cairo S, Bataller R, Sancho-Bru P, Martinez-Chantar ML, Marin JJG, Castaneda A, Armengol C, Berasain C, Fernandez-Barrena MG, Ávila MA.   +25 more
europepmc   +2 more sources

Plant communities of Italy. The vegetation prodrome [PDF]

, 2014
The Vegetation Prodrome of Italy was promoted in 2012 by the Italian "Ministry of Environment, Land and Sea Protection", in collaboration with the "Italian Society of Botany", to provide a comprehensive and systematic catalogue and description of Italian
Bartolo G, Bartolo G, Biondi E, Biondi E, Biondi E, Biondi E, Biondi E, Blasi C, Blasi C, Blasi C, Brullo S, C. BLASI, C. Lasen, Costa JC, D. Galdenzi, Dierschke H, E. Biondi, E. Carli, E. Del Vico, F. Taffetani, G. Sburlino, Galdenzi D, Géhu J-M, I. Anzellotti, I. Vagge, L. Facioni, L. Poldini, L. Zivkovic, M. Allegrezza, M. M. Azzella, Pesaresi S, R. Copiz, R. Gasparri, Rivas-Martínez S, Rivas-Martínez S, S. Casavecchia, S. Pesaresi, S. Zitti, Theurillat JP   +38 more
core   +1 more source

ESperANTO: utilizzo di nuove tecnologie didattiche per la formazione dell'industria dei contenuti

Italian Journal of Educational Technology, 2000
La FAST, Federazione delle associazioni scientifiche e tecniche, in collaborazione con l'Associazione italiana editori, ha realizzato il corso di formazione "Oltre il libro di testo" all'interno di un progetto Adapt II, in parte finanziato dalla ...
Rosaria Gandolfi
doaj   +1 more source

Distribution methods of ostomy and incontinence aids in the Italian healthcare setting: an evaluation questionnaire and social burden of direct distribution

Global & Regional Health Technology Assessment, 2022
Background: The distribution of ostomy and incontinence devices takes place through different modalities according to the regional provisions in force. A first possibility is represented by direct distribution by the local health authorities.
Filippo Rumi, Francesca Orsini, Vincenzo Falabella, Pier Raffaele Spena, Americo Cicchetti   +4 more
doaj   +1 more source