Results 121 to 130 of about 778,322 (318)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Generalized dimension function for $W^{\ast}$-algebras of infinite type [PDF]

, 1958
Jun Tomiyama
openalex   +1 more source

Combinatorial Screening for Europium Induced Defect Engineering in Titania Anodic Memristors

Advanced Materials Interfaces, EarlyView.
A Ti‐Eu thin‐film combinatorial libary (3‐17 at.% Eu) was fabricated by co‐sputtering and anodisation. Systematic screening revealed forming‐free memristors with analog switching, with compositions between 7‐17 at.% Eu showing improved endurance and multilevel resistive states.
Elena Atanasova, Andreas Greul, Ioan Mihail Ghitiu, Nicu Scarisoreanu, Achim Walter Hassel, Andrei Ionut Mardare   +5 more
wiley   +1 more source

PB2379: SPECIFIC ALTERATIONS IN MEMBRANE LIPID LEVELS AS POTENTIAL BIOMARKERS IN DLBCL PATIENTS

HemaSphere, 2023
Federica Loscocco, Federica DI Nolfo, Alessandro Isidori, Anna Sansone, Marino Brunori, Martina Chiarucci, Monica Calandrelli, Giuseppe Visani, Carla Ferreri   +8 more
doaj   +1 more source

Benchmarking Organic Photodiodes at the Noise Floor

Advanced Optical Materials, EarlyView.
A precise measurement framework based on a calibrated, ultra‐low‐noise automated setup with open‐source Python scripts enables accurate benchmarking of photodiodes. The unique combination of time‐dependent current measurement under dark conditions, followed by continuous‐wave faint illumination, facilitates reliable extraction of photocurrent near ...
Siddhartha Saggar, Giedrius Puidokas, Caroline Murawski   +2 more
wiley   +1 more source

Predicting severity in dengue patients - How far have we reached?

Journal of Dr. NTR University of Health Sciences
Background: Dengue fever (DF) is a viral infection endemic in more than 100 countries in the tropical and subtropical regions of the world, especially tropical Asia including India, Central and South America, and the Caribbean.
Shashikant Singh, Taruna Bansal, Neha Sharma, Vijay Kumar   +3 more
doaj   +1 more source

ASTS and AST Awards [PDF]

American Journal of Transplantation, 2003
openaire   +1 more source

Jordan ${\ast}$ -Derivations on ${C}^{\ast}$ -Algebras and $J{C}^{\ast}$ -Algebras

, 2008
We investigate Jordan ${\ast}$ -derivations on ${C}^{\ast}$ -algebras and Jordan ${\ast}$ -derivations on $J{C}^{\ast}$ -algebras associated with the following functional inequality $\Vert f(x)+f(y)+kf(z)\Vert \leq \Vert kf((x+y)/k+z)\Vert $ for some integer $k$ greater than 1.
Su An, Jong, Cui, Jianlian, Park, Choonkil   +2 more
openaire   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

Advanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source